Commencing search, please wait for results.

BLASTP 2.0.6 [Sept-16-1998]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|2317723 Polycomb 2 homolog
         (558 letters)

Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
           338,166 sequences; 103,251,576 total letters

Searching..................................................done

If you have any problems or questions with the results of this search
please refer to the BLAST FAQs

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

gi|2317723  (AF013956) Polycomb 2 homolog [Homo sapiens]              887  0.0
gi|2781392  (U63387) transcriptional repressor Mpc2 [Mus musculus]    803  0.0
gnl|PID|d1034368  (AB005619) chromobox protein (CHCB3) [Gallus g...   541  e-153
pir||I51693  XPolycomb - African clawed frog >gi|1086556 (U39929...   420  e-116
gi|1945453  (U94344) Polycomb 2 homolog [Homo sapiens]                138  9e-32
gi|3860185  (AF101438) Polycomb homolog Pc1 [Xenopus laevis]          114  2e-24
sp|P30658|MOD3_MOUSE  MODIFIER 3 PROTEIN (M33) >gi|110709|pir||S...   111  9e-24
gnl|PID|e324403  (Y13274) M33 polycomb-like protein [Mus musculus]    110  2e-23
sp|P26017|PC_DROME  POLYCOMB PROTEIN >gi|103306|pir||A38565 poly...    74  2e-12
gnl|PID|d1026845  (D83719) polycomb-like protein [Daucus carota]       66  4e-10
sp|P34618|YO82_CAEEL  HYPOTHETICAL 33.8 KD PROTEIN ZK1236.2 IN C...    63  5e-09
sp|P45973|HP1A_HUMAN  HETEROCHROMATIN PROTEIN 1 HOMOLOG ALPHA (H...    62  1e-08
gi|886063  (U26311) HP1Hs-alpha [Homo sapiens]                         62  1e-08
sp|Q13185|HP1G_HUMAN  HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (H...    61  2e-08
sp|Q61686|HP1A_MOUSE  HETEROCHROMATIN PROTEIN 1 HOMOLOG ALPHA (H...    61  2e-08
sp|P23197|HP1B_HUMAN  HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (H...    60  4e-08
pdb|1AP0|    Structure Of The Chromatin Binding (Chromo) Domain ...    60  4e-08
gnl|PID|d1034366  (AB005617) chromobox protein (CHCB1) [Gallus g...    60  4e-08
gi|2454534  (AF009821) heterochromatin protein 1 gamma [Xenopus ...    59  8e-08
sp|P23198|HP1G_MOUSE  HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (H...    59  8e-08
sp|P05205|HP1_DROME  HETEROCHROMATIN PROTEIN 1 (HP1) (NONHISTONE...    58  1e-07
gnl|PID|d1034367  (AB005618) chromobox protein (CHCB2) [Gallus g...    58  1e-07
pir||A25081  nonhistone chromosomal protein - fruit fly (Drosoph...    57  2e-07
sp|P29227|HP1_DROVI  HETEROCHROMATIN PROTEIN 1 (HP1) >gi|479842|...    56  7e-07
gi|2707897  (AF038153) elongation-like factor [Candida albicans]       51  2e-05
gi|3702834  (AF056580) heterochromatin protein 1 homolog [Caenor...    50  4e-05
pir||S65245  hypothetical protein YPL226w - yeast (Saccharomyces...    49  8e-05
pir||S60179  pol polyprotein homolog - fungus (Fusarium oxysporu...    47  2e-04
sp|O14646|CHD1_HUMAN  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN ...    47  3e-04
gi|3342716  (AF000981) testis-specific ChromoDomain Y isoform 1 ...    46  6e-04
gi|3719261  (AF079405) heterochromatin-associated protein 1-like...    46  6e-04
gi|2501846  (AF004397) chromo-helicase-DNA-binding on the Z chro...    46  6e-04
pir||A47392  chromodomain-helicase-DNA-binding protein, CHD-1 - ...    45  0.001
sp|P40201|CHD1_MOUSE  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN ...    45  0.001
gi|2707217  (AF019969) Su(var)3-9 homolog [Mus musculus]               45  0.001
gi|1397245  (U61944) coded for by C. elegans cDNA yk19a7.5; code...    45  0.001
gi|2707215  (AF019968) Su(var)3-9 homolog [Homo sapiens]               43  0.005
sp|O14647|CHD2_HUMAN  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN ...    42  0.011
gi|818888  (U25814) chromodomain protein [Plasmodium falciparum]       41  0.014
sp|Q10103|YAQ2_SCHPO  HYPOTHETICAL 108.7 KD PROTEIN C18G6.02C IN...    41  0.025
pir||S23571  hypothetical protein - fungus (Cladosporium fulvum)...    40  0.042
sp|P40381|SWI6_SCHPO  SWI6 PROTEIN >gi|510930 (X71783) swi6 gene...    39  0.055
gi|3510505  (AF030881) pol polyprotein [Fugu rubripes]                 39  0.072
gi|538067  (M77661) putative pol polyprotein [Magnaporthe grisea]      39  0.095
gi|1448983  (L77907) chromodomain-helicase-DNA-binding protein [...    38  0.12
gi|1519343  (U66363) Pdd1p [Tetrahymena thermophila] >gi|1519345...    38  0.12
gi|726375  (U23169) No definition line found [Caenorhabditis ele...    38  0.16
gnl|PID|e351430  (Z99568) elongation factor [Schizosaccharomyces...    38  0.21
gnl|PID|e1332815  (AL031907) hypothetical protein [Schizosacchar...    36  0.48
sp|P45975|SUV9_DROME  SU(VAR)3-9 PROTEIN >gi|1079141|pir||S47004...    36  0.63
sp|P32657|CHD1_YEAST  CHD1 PROTEIN >gi|320737|pir||S30818 hypoth...    36  0.82
gnl|PID|e1347595  (Z92970) predicted using Genefinder; Similarit...    36  0.82
gi|2766715  (AF039365) chromomethylase [Arabidopsis arenosa] >gi...    35  1.1
gnl|PID|e1311690  (AJ007840) Clr4 protein [Schizosaccharomyces p...    35  1.1
gi|3170999  (AF061854) Clr4p [Schizosaccharomyces pombe]               35  1.4
pir||S51421  hypothetical protein YLR176c - yeast (Saccharomyces...    34  1.8
sp|P48743|RFXL_YEAST  HYPOTHETICAL 90.6 KD PROTEIN IN CBF5-DKA1 ...    34  1.8
gi|2529682  (AC002535) unknown protein [Arabidopsis thaliana]          34  1.8
sp|P45968|YNZ8_CAEEL  HYPOTHETICAL 37.7 KD PROTEIN T09A5.8 IN CH...    34  2.4
gi|2291229  (AF016427) No definition line found [Caenorhabditis ...    34  2.4
gnl|PID|d1025779  (AB007887) KIAA0427 [Homo sapiens]                   34  2.4
gnl|PID|d1022385  (D88815) beta-1,3-glucan synthase catalytic su...    34  3.2
gi|2289904  (AC002397) DRPLA [Mus musculus]                            34  3.2
sp|Q99014|KPC1_TRIRE  PROTEIN KINASE C-LIKE >gi|2133306|pir||S61...    34  3.2
gnl|PID|e4805  (X07517) proline-rich protein (51 is 2nd base in ...    34  3.2
gi|1531633  (U60591) kuzbanian [Drosophila melanogaster]               33  4.2
gnl|PID|d1014140  (D87744) DRPLA protein [Mus musculus]                33  4.2
pir||A49873  inositol 1,4,5-triphosphate receptor, type 3 - huma...    33  5.4
pir||I78883  retinoblastoma binding protein 1 isoform II - human...    33  5.4
pir||I58390  retinoblastoma binding protein 1 isoform I - human ...    33  5.4
bbs|127743  (S57162) retinoblastoma binding protein 1 isoform II...    33  5.4
gnl|PID|d1005927  (D26351) human type 3 inositol 1,4,5-trisphosp...    33  5.4
gi|2454532  (AF009820) heterochromatin protein 1 alpha [Xenopus ...    33  5.4
pir||B42997  retinoblastoma-associated protein 2 - human               33  5.4
gi|2702442  (AF038614) contains similarity to Lentinula edodes M...    33  5.4
pir||A27307  proline-rich phosphoprotein (gene PRH1, Db allele) ...    32  7.1
sp|P54259|DRPL_HUMAN  ATROPHIN-1 (DENTATORUBRAL-PALLIDOLUYSIAN A...    32  7.1
gi|915326  (U23851) atrophin-1 [Homo sapiens]                          32  7.1
pir||S50832  DRPLA protein - human                                     32  7.1
gi|1118175  (U41992) coded for by C. elegans cDNA yk117d5.5; cod...    32  7.1
gnl|PID|d1008115  (D38529) DRPLA protein [Homo sapiens]                32  7.1
sp|P29374|RBB1_HUMAN  RETINOBLASTOMA BINDING PROTEIN 1 (RBBP-1) ...    32  9.3
gnl|PID|e238657  (Z71926) neural cell adhesion molecule L1 [Fugu...    32  9.3
gnl|PID|e1344068  (Z72503) similar to HMG (high mobility group) ...    32  9.3

 gi|2317723 (AF013956) Polycomb 2 homolog [Homo sapiens]
           Length = 558
           
 Score =  887 bits (2268), Expect = 0.0
 Identities = 445/558 (79%), Positives = 445/558 (79%)

Query: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
           MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR
Sbjct: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60

Query: 61  ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 120
           ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY
Sbjct: 61  ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 120

Query: 121 ELNSKKHHQYQPHSKEGKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPS 180
           ELNSKKHHQYQPHSKEGKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPS
Sbjct: 121 ELNSKKHHQYQPHSKEGKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPS 180

Query: 181 PTCPDLGAKSHPPDKWAQGAGAKGYLXXXXXXXXXXXXXXXXXXXXXXNGMMPAPKEAVT 240
           PTCPDLGAKSHPPDKWAQGAGAKGYL                      NGMMPAPKEAVT
Sbjct: 181 PTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEAVT 240

Query: 241 GNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADER 300
           GNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADER
Sbjct: 241 GNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADER 300

Query: 301 HPPADRTFXXXXXXXXXXXXXXXXXXXXXXSGVSDPQPQDAGSRKLSPTKEAFGEQPLQL 360
           HPPADRTF                      SGVSDPQPQDAGSRKLSPTKEAFGEQPLQL
Sbjct: 301 HPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPLQL 360

Query: 361 TTKPDLLAWDPARNTXXXXXXXXXXXXXXXXXXXXXXXAVGLNLSHVRKRCLSETHGERE 420
           TTKPDLLAWDPARNT                       AVGLNLSHVRKRCLSETHGERE
Sbjct: 361 TTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGERE 420

Query: 421 PCKKRLTARSISTPTCLGGSXXXXXXXXXXXXXXXXXXEVILLDSDLDEPIDLRSVKSRS 480
           PCKKRLTARSISTPTCLGGS                  EVILLDSDLDEPIDLRSVKSRS
Sbjct: 421 PCKKRLTARSISTPTCLGGSPAAERPADLPPAAALRQPEVILLDSDLDEPIDLRSVKSRS 480

Query: 481 EAGEPPSSLQVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXQDEPAESLSEFKPFFGNIII 540
           EAGEPPSSLQVK                            QDEPAESLSEFKPFFGNIII
Sbjct: 481 EAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNIII 540

Query: 541 TDVTANCLTVTFKEYVTV 558
           TDVTANCLTVTFKEYVTV
Sbjct: 541 TDVTANCLTVTFKEYVTV 558

 gi|2781392 (U63387) transcriptional repressor Mpc2 [Mus musculus]
           Length = 551
           
 Score =  803 bits (2051), Expect = 0.0
 Identities = 415/562 (73%), Positives = 423/562 (74%), Gaps = 15/562 (2%)

Query: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
           MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR
Sbjct: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60

Query: 61  ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 120
           ERQEQLMGYRKRGPKP PLVVQVPTFARRSNVLTGLQDSS DNRAKL+LG QGKGQGHQY
Sbjct: 61  ERQEQLMGYRKRGPKPNPLVVQVPTFARRSNVLTGLQDSSADNRAKLELGTQGKGQGHQY 120

Query: 121 ELNSKKHHQYQPHSKE--GKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA 178
           ELNSKKHHQYQPHSKE  GKP P  KSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA
Sbjct: 121 ELNSKKHHQYQPHSKERSGKPPPARKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA 180

Query: 179 PSPTCPDLGAKSHPPDKWAQGAGAKGYLXXXXXXXXXXXXXXXXXXXXXXNGMMPAPKEA 238
           PSPTCPDLG KSHPPDKWA GA AKGYL                      NGM PAPKEA
Sbjct: 181 PSPTCPDLGTKSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGMTPAPKEA 240

Query: 239 VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAAD 298
           VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGE AEGEARSPSHKKRAA+
Sbjct: 241 VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEAAEGEARSPSHKKRAAE 300

Query: 299 ERHPPADRTFXXXXXXXXXXXXXXXXXXXXXXSGVS-DPQPQDAGSRKLSPTKEAFGEQP 357
           ERHP  DRTF                      + VS D QPQD GSRKLSPTKEAFGEQP
Sbjct: 301 ERHPQGDRTFKKAAGASEEKKAEVPCKRREEEALVSGDAQPQDLGSRKLSPTKEAFGEQP 360

Query: 358 LQLTTKPDLLAWDPARNTXXXXXXXXXXXXXXXXXXXXXXXAVGLNLSHVRKRCLSETHG 417
           LQLTTKPDLLAWDPAR++                        VGLNLSH RKRCLSETHG
Sbjct: 361 LQLTTKPDLLAWDPARSS------HPPAHHHHHHHHHHHHHTVGLNLSHARKRCLSETHG 414

Query: 418 EREPCKKRLTARSISTPTCLGGS-XXXXXXXXXXXXXXXXXXEVILLDSDLDEPIDLRSV 476
           EREPCKKRLTARSISTPTCLGGS                   EVILLDSDLDEPIDLR V
Sbjct: 415 EREPCKKRLTARSISTPTCLGGSPVSEHPANVSPTAASLPQPEVILLDSDLDEPIDLRCV 474

Query: 477 KSRSEAGEPPSSLQVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXQDEPAESLSEFKPFFG 536
           K RS+AGEPPS+LQVK                            Q+EP E LSEFKPFFG
Sbjct: 475 KMRSDAGEPPSTLQVK-----PEAPAVAAVVAPAPASEKPPAEAQEEPVEPLSEFKPFFG 529

Query: 537 NIIITDVTANCLTVTFKEYVTV 558
           NIIITDVTANCLTVTFKEYVTV
Sbjct: 530 NIIITDVTANCLTVTFKEYVTV 551

 gnl|PID|d1034368 (AB005619) chromobox protein (CHCB3) [Gallus gallus]
           Length = 523
           
 Score =  541 bits (1379), Expect = e-153
 Identities = 323/576 (56%), Positives = 347/576 (60%), Gaps = 71/576 (12%)

Query: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
           MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR
Sbjct: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60

Query: 61  ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 120
           ERQEQLMGYRKRGPKPKPLVVQ+P+FARRSN+LTGLQD + D R KLDLG+ GK Q HQY
Sbjct: 61  ERQEQLMGYRKRGPKPKPLVVQLPSFARRSNILTGLQDPTVDTRPKLDLGSSGKSQQHQY 120

Query: 121 ELNSKKHHQYQPHSKE-GKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAP 179
           ELNSKKHHQYQP+ KE G        GKYYYQLNSKKHH YQPDPKMY+  Y    KE  
Sbjct: 121 ELNSKKHHQYQPNGKESGVKHQSHSKGKYYYQLNSKKHHHYQPDPKMYEPHYHPSGKEPQ 180

Query: 180 SPTCPD-----LGAKSHPPDKWAQGAGAKGYLXXXXXXXXXXXXXXXXXXXXXXNGMMPA 234
              C D     LGA    PDKWA GA AK  L                      +G  P 
Sbjct: 181 GQACLDSTKSPLGAH---PDKWAHGA-AKNLL---GPVKNLAAESKNGAEKNLSSGTGPP 233

Query: 235 PKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKK 294
           P++ VT NG+GGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGE     A      K
Sbjct: 234 PRDRVTSNGLGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEPPRKRAPEERTAK 293

Query: 295 RAADE-----RHPPADRTFXXXXXXXXXXXXXXXXXXXXXXSGVSDPQPQDAGSRKLSPT 349
           +  +E     R P  +R                                   G RK SP 
Sbjct: 294 KGGEEKLEAWRKPGEERAVGSNGLSAAEGESRQPAAEL------------QEGPRKPSPG 341

Query: 350 KE---AFGEQPLQLTTKPDLLAW--DPARNTXXXXXXXXXXXXXXXXXXXXXXXAVGLNL 404
           KE      EQPLQLTTKPDL+ W   P R                         ++GLNL
Sbjct: 342 KELPLPVAEQPLQLTTKPDLVPWSLSPGRE--------------------HSPSSMGLNL 381

Query: 405 SH--VRKRCLSETHGEREPCKKRLTARSISTPTCLGGSXXXXXXXXXXXXXXXXXXEVIL 462
           S    RKRCLSE HG+REP KKRLT+RSIS PTCLG                    EVIL
Sbjct: 382 SSPGARKRCLSEPHGDREPGKKRLTSRSISAPTCLGPE----------RPELPAQPEVIL 431

Query: 463 LDSDLDEPIDLRSVKSRSEAGEPPSSLQVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXQD 522
           LDSDLDEPIDLR VK R+E GE  + +QVK                            ++
Sbjct: 432 LDSDLDEPIDLRCVKPRAE-GE-AALVQVK--PEEPPAPAEQPPVEPPQQPRQAAEEEEE 487

Query: 523 EPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 558
           E AE L EFKPFFGNIIITDVTANCLTVTFKEYVTV
Sbjct: 488 EEAEGLREFKPFFGNIIITDVTANCLTVTFKEYVTV 523

 pir||I51693 XPolycomb - African clawed frog >gi|1086556 (U39929) XPolycomb
           [Xenopus laevis]
           Length = 521
           
 Score =  420 bits (1068), Expect = e-116
 Identities = 263/579 (45%), Positives = 314/579 (53%), Gaps = 79/579 (13%)

Query: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
           MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWS KYNTWEPEENILDPRLL+AFQNR
Sbjct: 1   MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSSKYNTWEPEENILDPRLLVAFQNR 60

Query: 61  ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 120
           ERQEQ+MGYRKRGPKPK  +V +P+FARRSNVL+GL DSS +NR KLDLG   K   HQY
Sbjct: 61  ERQEQIMGYRKRGPKPKNNLVSMPSFARRSNVLSGLHDSSGENRTKLDLGPIPKS--HQY 118

Query: 121 ELNSKKHHQYQPHSKE-GKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQY-------- 171
           +LNSKKHHQYQP  K+  +        KYYYQLNSKKHH YQPDPK+Y+ QY        
Sbjct: 119 QLNSKKHHQYQPSGKDHNEKHHSSNKKKYYYQLNSKKHHHYQPDPKLYE-QYTIEKESQI 177

Query: 172 ----QGGHKEAPSPT-CPDLGAK-SHPPDKWAQGAGAKGYLXXXXXXXXXXXXXXXXXXX 225
               +  H+++ + T   D+G +  +  D    G    G                     
Sbjct: 178 STDVRNRHRDSLTHTQAADMGTQLKNGTDSVISGPERNGICNGVSSSPSTEMSSSPSTE- 236

Query: 226 XXXNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEG 285
                +  +P   +  +G+GGKMKIVKNKNKNGRIVIVMSKYMENGMQ+VKIKS   +E 
Sbjct: 237 -----LSSSPSTELPSSGVGGKMKIVKNKNKNGRIVIVMSKYMENGMQSVKIKS---SEE 288

Query: 286 EARSPSHKKRAADERHPPADRTFXXXXXXXX--XXXXXXXXXXXXXXSGVSDPQPQDAGS 343
           +      ++R         D+T                           V       AG 
Sbjct: 289 DCDMGDVRRRFDSPGTLNGDKTCTAQEEKTEHWKKRVESRVKIHEGSKSVDKGSVHLAGL 348

Query: 344 RK-LSPTKEAFGEQPLQLTTKPDLLAWDPARNTXXXXXXXXXXXXXXXXXXXXXXXAVGL 402
           R+  S   E   +QPLQLTTK   +   P  N                           L
Sbjct: 349 RRTYSTASETLNDQPLQLTTKSSHV---PMPNRTRSPVYAGEPYN-------------DL 392

Query: 403 NLSHVRKRCLSETHGEREPCKKRLTARSISTP---TCLGGSXXXXXXXXXXXXXXXXXXE 459
             ++ RKRCLSE +G +E CKK LT+RS+S P    C GG                   +
Sbjct: 393 VYTNPRKRCLSEANGNKELCKKTLTSRSVSAPGIVECKGG--------LTPLNVPLQEPD 444

Query: 460 VILLDSDLDEPIDLRSVKSRSEAGEPPSSLQVKXXXXXXXXXXXXXXXXXXXXXXXXXXX 519
           +ILLDSDLDEPIDLR VKSR ++ +     +++                           
Sbjct: 445 IILLDSDLDEPIDLRCVKSRCDSDQEVDKPEIQVTQNPQSVDVDVCE------------- 491

Query: 520 XQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 558
                    S+FKPFFGNI+ITDVTANCLTVTFKEY+TV
Sbjct: 492 ---------SQFKPFFGNIVITDVTANCLTVTFKEYITV 521

 gi|1945453 (U94344) Polycomb 2 homolog [Homo sapiens]
           Length = 104
           
 Score =  138 bits (344), Expect = 9e-32
 Identities = 72/100 (72%), Positives = 72/100 (72%)

Query: 459 EVILLDSDLDEPIDLRSVKSRSEAGEPPSSLQVKXXXXXXXXXXXXXXXXXXXXXXXXXX 518
           EVILLDSDLDEPIDLRSVKSRSEAGEPPSSLQVK                          
Sbjct: 5   EVILLDSDLDEPIDLRSVKSRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPA 64

Query: 519 XXQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 558
             QDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV
Sbjct: 65  EAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 104

 gi|3860185 (AF101438) Polycomb homolog Pc1 [Xenopus laevis]
           Length = 471
           
 Score =  114 bits (282), Expect = 2e-24
 Identities = 58/107 (54%), Positives = 74/107 (68%), Gaps = 6/107 (5%)

Query: 2   ELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRE 61
           EL AVGE VFA E I  KR+RKG  EYLVKWRGWS K+N+WEPEENILDPRLL+AFQ RE
Sbjct: 3   ELSAVGEQVFAAECILSKRLRKGTAEYLVKWRGWSSKHNSWEPEENILDPRLLVAFQKRE 62

Query: 62  RQEQLMGYRKRGPKP-----KPLVVQVPTFARRSNVLTGLQDSSTDN 103
           ++++L   RKRG +P     K +   +P  A+ S+  +    SS+ +
Sbjct: 63  QEKELRN-RKRGKRPRGRPRKNVETDIPLKAKSSSSSSSSSSSSSSS 108

 sp|P30658|MOD3_MOUSE MODIFIER 3 PROTEIN (M33) >gi|110709|pir||S23796 modifier-3 protein
           - mouse >gi|52977 (X62537) modifier 3 (M33) [Mus
           musculus]
           Length = 519
           
 Score =  111 bits (276), Expect = 9e-24
 Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 4/147 (2%)

Query: 2   ELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRE 61
           EL +VGE VFA E I  KR+RKG++EYLVKWRGWS K+N+WEPEENILDPRLL+AFQ +E
Sbjct: 3   ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 62

Query: 62  RQEQLMGYRKRGPKPKPLV---VQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGH 118
            ++++   RKRG +P+          + +RRS +      S + + +             
Sbjct: 63  HEKEVQN-RKRGKRPRGRPRKHTATSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121

Query: 119 QYELNSKKHHQYQPHSKEGKPRPPGKS 145
           + E +S    +  P  +E  P P  K+
Sbjct: 122 EEEDDSDLDSKRGPRGRETHPVPQKKA 148

 gnl|PID|e324403 (Y13274) M33 polycomb-like protein [Mus musculus]
           Length = 520
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 4/147 (2%)

Query: 2   ELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRE 61
           EL +VGE VFA E I  KR+RKG++EYLVKWRGWS K+N+WEPEENILDPRLL+AFQ +E
Sbjct: 4   ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 63

Query: 62  RQEQLMGYRKRGPKPKPLV---VQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGH 118
            ++++   RKRG +P+          + +RRS +      S + + +             
Sbjct: 64  HEKEVQN-RKRGKRPRGRPRKHTVTSSCSRRSKLKEPDAPSKSKSGSSSSSSTSSSSSSD 122

Query: 119 QYELNSKKHHQYQPHSKEGKPRPPGKS 145
           + E +S    +  P  +E  P P  K+
Sbjct: 123 EEEDDSDLDSKGGPRGRETHPVPQKKA 149

 sp|P26017|PC_DROME POLYCOMB PROTEIN >gi|103306|pir||A38565 polycomb (Pc) protein -
          fruit fly (Drosophila melanogaster) >gi|603986 (X55702)
          polycomb protein [Drosophila melanogaster]
          Length = 390
          
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 33/72 (45%), Positives = 47/72 (64%), Gaps = 3/72 (4%)

Query: 10 VFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQE---QL 66
          V+A E I +KR++KG VEY VKW+GW+ +YNTWEPE NILD RL+  ++   +       
Sbjct: 25 VYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGTPSK 84

Query: 67 MGYRKRGPKPKP 78
           G +K+  +P P
Sbjct: 85 RGIKKKEKEPDP 96

 gnl|PID|d1026845 (D83719) polycomb-like protein [Daucus carota]
           Length = 392
           
 Score = 66.3 bits (159), Expect = 4e-10
 Identities = 31/72 (43%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 4   PAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENI-LDPRLLIAFQNRER 62
           P + E  F +E I +KR++KG V+YLVKWRGW    NTWEP E++   P ++ AF+ R+ 
Sbjct: 48  PELPEGFFEIEHIRRKRVKKGEVQYLVKWRGWPESANTWEPVEHLEAVPDVVDAFEQRQS 107

Query: 63  QEQLMGYRKRGP 74
            +     RK  P
Sbjct: 108 GKHKSSKRKGRP 119

 sp|P34618|YO82_CAEEL HYPOTHETICAL 33.8 KD PROTEIN ZK1236.2 IN CHROMOSOME III
          >gi|630762|pir||S44897 ZK1236.2 protein -
          Caenorhabditis elegans >gi|289753 (L13200) homology
          with nucleolin protein; putative [Caenorhabditis
          elegans]
          Length = 304
          
 Score = 62.8 bits (150), Expect = 5e-09
 Identities = 27/57 (47%), Positives = 40/57 (69%)

Query: 5  AVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRE 61
          A G  ++ VESI + R +KG+ E+ +KW G+   +N+WEP+ENI+DP L+ AF  RE
Sbjct: 2  ADGSELYTVESILEHRKKKGKSEFYIKWLGYDHTHNSWEPKENIVDPTLIEAFFTRE 58

 sp|P45973|HP1A_HUMAN HETEROCHROMATIN PROTEIN 1 HOMOLOG ALPHA (HP1 ALPHA) (ANTIGEN P25)
          >gi|184311 (L07515) [Human heterochromatin protein
          homologue (HP1) mRNA, complete cds.], gene product
          [Homo sapiens] >gi|386087|bbs|133162 (S62077) HP1Hs
          alpha=25 kda chromosomal autoantigen [human, Peptide,
          191 aa] [Homo sapiens]
          Length = 191
          
 Score = 61.7 bits (147), Expect = 1e-08
 Identities = 28/71 (39%), Positives = 44/71 (61%), Gaps = 6/71 (8%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLM 67
          E  + VE +  +R+ KG+VEYL+KW+G+S ++NTWEPE+N+  P L+  F  + ++    
Sbjct: 17 EEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK---- 72

Query: 68 GYRKRGPKPKP 78
             K G   KP
Sbjct: 73 --MKEGENNKP 81

 gi|886063 (U26311) HP1Hs-alpha [Homo sapiens]
          Length = 190
          
 Score = 61.7 bits (147), Expect = 1e-08
 Identities = 28/71 (39%), Positives = 44/71 (61%), Gaps = 6/71 (8%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLM 67
          E  + VE +  +R+ KG+VEYL+KW+G+S ++NTWEPE+N+  P L+  F  + ++    
Sbjct: 16 EEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK---- 71

Query: 68 GYRKRGPKPKP 78
             K G   KP
Sbjct: 72 --MKEGENNKP 80

 sp|Q13185|HP1G_HUMAN HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (HP1 GAMMA) (MODIFIER 2
          PROTEIN) >gi|1773227 (U26312) HP1Hs-gamma [Homo
          sapiens]
          Length = 173
          
 Score = 61.3 bits (146), Expect = 2e-08
 Identities = 31/69 (44%), Positives = 41/69 (58%), Gaps = 4/69 (5%)

Query: 11 FAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYR 70
          F VE +  +R+  G+VEY +KW+G++   NTWEPEEN+  P L+ AF N     Q  G  
Sbjct: 20 FVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLN----SQKAGKE 75

Query: 71 KRGPKPKPL 79
          K G K K L
Sbjct: 76 KDGTKRKSL 84

 sp|Q61686|HP1A_MOUSE HETEROCHROMATIN PROTEIN 1 HOMOLOG ALPHA (HP1 ALPHA)
          >gi|1480108|gnl|PID|e256810 (X99641) HP1 alpha protein
          [Mus musculus]
          Length = 191
          
 Score = 60.9 bits (145), Expect = 2e-08
 Identities = 28/71 (39%), Positives = 44/71 (61%), Gaps = 6/71 (8%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLM 67
          E  + VE +  +R+ KG+VEYL+KW+G+S ++NTWEPE+N+  P L+  F  + ++    
Sbjct: 17 EEEYVVEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK---- 72

Query: 68 GYRKRGPKPKP 78
             K G   KP
Sbjct: 73 --MKEGENNKP 81

 sp|P23197|HP1B_HUMAN HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (HP1 BETA) (MODIFIER 1
          PROTEIN) (M31) (HETEROCHROMATIN PROTEIN P25)
          >gi|284976|pir||S26847 modifier-1 protein - mouse
          >gi|53163 (X56690) modifier 1 [Mus musculus]
          >gi|1177845 (U35451) heterochromatin protein p25 [Homo
          sapiens]
          Length = 185
          
 Score = 59.7 bits (142), Expect = 4e-08
 Identities = 25/55 (45%), Positives = 38/55 (68%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRER 62
          E  + VE +  +R+ KG+VEYL+KW+G+S + NTWEPEEN+  P L+  F   ++
Sbjct: 18 EEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQK 72

 pdb|1AP0|   Structure Of The Chromatin Binding (Chromo) Domain From Mouse
          Modifier Protein 1, Nmr, 26 Structures
          Length = 73
          
 Score = 59.7 bits (142), Expect = 4e-08
 Identities = 25/55 (45%), Positives = 38/55 (68%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRER 62
          E  + VE +  +R+ KG+VEYL+KW+G+S + NTWEPEEN+  P L+  F   ++
Sbjct: 11 EEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQK 65

 gnl|PID|d1034366 (AB005617) chromobox protein (CHCB1) [Gallus gallus]
          Length = 185
          
 Score = 59.7 bits (142), Expect = 4e-08
 Identities = 25/55 (45%), Positives = 38/55 (68%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRER 62
          E  + VE +  +R+ KG+VEYL+KW+G+S + NTWEPEEN+  P L+  F   ++
Sbjct: 18 EEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQK 72

 gi|2454534 (AF009821) heterochromatin protein 1 gamma [Xenopus laevis]
          Length = 171
          
 Score = 58.9 bits (140), Expect = 8e-08
 Identities = 24/52 (46%), Positives = 36/52 (69%)

Query: 11 FAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRER 62
          F VE +  +R+  G+VEY +KW+G++   NTWEPEEN+  P L+ AF N ++
Sbjct: 17 FVVEKVMDRRVVNGKVEYYLKWKGFTDSDNTWEPEENLDCPELIEAFLNSQK 68

 sp|P23198|HP1G_MOUSE HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA (HP1 GAMMA) (MODIFIER 2
          PROTEIN) (M32) >gi|284977|pir||S26846 modifier-2
          protein - mouse >gi|53165 (X56683) modifier 2 [Mus
          musculus]
          Length = 173
          
 Score = 58.9 bits (140), Expect = 8e-08
 Identities = 30/69 (43%), Positives = 40/69 (57%), Gaps = 4/69 (5%)

Query: 11 FAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYR 70
          F VE +  +R+  G+VEY +KW+G++   NTWEPEEN+  P L+  F N     Q  G  
Sbjct: 20 FVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEDFLN----SQKAGKE 75

Query: 71 KRGPKPKPL 79
          K G K K L
Sbjct: 76 KDGTKRKSL 84

 sp|P05205|HP1_DROME HETEROCHROMATIN PROTEIN 1 (HP1) (NONHISTONE CHROMOSOMAL PROTEIN
           C1A9 ANTIGEN) >gi|103192|pir||A39268
           heterochromatin-specific chromosomal protein 1 - fruit
           fly (Drosophila melanogaster) >gi|157641 (M57574) HP-1
           [Drosophila melanogaster]
           Length = 206
           
 Score = 58.2 bits (138), Expect = 1e-07
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 9/99 (9%)

Query: 8   EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLM 67
           E  +AVE I  +R+RKG+VEY +KW+G+    NTWEPE N+    L+  ++   + E+  
Sbjct: 21  EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKS 80

Query: 68  GYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAK 106
              K+           P+ + ++    G   SST   +K
Sbjct: 81  AASKK---------DRPSSSAKAKETQGRASSSTSTASK 110

 gnl|PID|d1034367 (AB005618) chromobox protein (CHCB2) [Gallus gallus]
          Length = 174
          
 Score = 58.2 bits (138), Expect = 1e-07
 Identities = 24/52 (46%), Positives = 36/52 (69%)

Query: 11 FAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRER 62
          F VE +  +R+  G+VEY +KW+G++   NTWEPEEN+  P L+ AF N ++
Sbjct: 20 FVVEKVLDRRVVNGKVEYYLKWKGFTDADNTWEPEENLDCPELIEAFLNSQK 71

 pir||A25081 nonhistone chromosomal protein - fruit fly (Drosophila
           melanogaster) >gi|157026 (M14131) C1A9 antigen
           [Drosophila melanogaster]
           Length = 161
           
 Score = 57.4 bits (136), Expect = 2e-07
 Identities = 31/84 (36%), Positives = 45/84 (52%), Gaps = 1/84 (1%)

Query: 8   EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLM 67
           E  +AVE I  +R+RKG+VEY +KW+G+    NTWEPE N LD + LI      R+++  
Sbjct: 21  EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENN-LDCQDLIQQYEASRKDEEK 79

Query: 68  GYRKRGPKPKPLVVQVPTFARRSN 91
               +  +P        T  R S+
Sbjct: 80  SAASKKDRPSSSAKAKETQGRASS 103

 sp|P29227|HP1_DROVI HETEROCHROMATIN PROTEIN 1 (HP1) >gi|479842|pir||S35522
          heterochromatin protein 1 - fruit fly (Drosophila
          virilis) >gi|157745 (M88753) heterochromatin protein-1
          [Drosophila virilis]
          Length = 213
          
 Score = 55.8 bits (132), Expect = 7e-07
 Identities = 27/58 (46%), Positives = 39/58 (66%), Gaps = 1/58 (1%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQ 65
          E  +AVE I  +R+RKG+VEY +KW+G++   NTWEPE N LD + LI      R+++
Sbjct: 21 EEEYAVEKILDRRVRKGKVEYYLKWKGYAETENTWEPEGN-LDCQDLIQQYELSRKDE 77

 gi|2707897 (AF038153) elongation-like factor [Candida albicans]
           Length = 1191
           
 Score = 50.8 bits (119), Expect = 2e-05
 Identities = 23/66 (34%), Positives = 40/66 (59%), Gaps = 3/66 (4%)

Query: 12  AVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILD---PRLLIAFQNRERQEQLMG 68
           A+E++  ++  K   +Y VKW+ W PKYN+W P+E +L+    +L+  F + E   + +G
Sbjct: 935 AIEALVGRQKLKKSFQYEVKWKYWLPKYNSWVPKEVLLEHGFDKLIQKFDDHEASREGLG 994

Query: 69  YRKRGP 74
           YR+  P
Sbjct: 995 YRELTP 1000

 gi|3702834 (AF056580) heterochromatin protein 1 homolog [Caenorhabditis
           elegans] >gi|3878389|gnl|PID|e1347981 (Z70210) predicted
           using Genefinder; Similarity to Mouse modifier 2 protein
           (SW:MOD2_MOUSE); cDNA EST yk432c11.3 comes from this
           gene; cDNA EST yk432c11.5 comes from this gene
           [Caenorhabditis elegans]
           Length = 184
           
 Score = 50.0 bits (117), Expect = 4e-05
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 9   HVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMG 68
           +VF VE +  KR+ +G  EY +KW+G+     +WEP EN+   R++   Q  E++     
Sbjct: 35  NVFVVEKVLNKRLTRGGSEYYIKWQGFPESECSWEPIENLQCDRMI---QEYEKEAAKRT 91

Query: 69  YRKRGPKPKP 78
            RKR   P+P
Sbjct: 92  TRKRRYSPQP 101

 pir||S65245 hypothetical protein YPL226w - yeast (Saccharomyces cerevisiae)
            >gi|1370468|gnl|PID|e247071 (Z73582) ORF YPL226w
            [Saccharomyces cerevisiae]
            Length = 1196
            
 Score = 48.8 bits (114), Expect = 8e-05
 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 3/66 (4%)

Query: 12   AVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILD---PRLLIAFQNRERQEQLMG 68
            A+E+I  ++  K   +Y VKW+ W PKYN+W P++ +++    +L+  F + E   + +G
Sbjct: 943  AIEAIVGRQKLKKSFQYEVKWKYWKPKYNSWVPKDVLVEHGFEKLVQKFDDHEASREGLG 1002

Query: 69   YRKRGP 74
            YR+  P
Sbjct: 1003 YRELIP 1008

 pir||S60179 pol polyprotein homolog - fungus (Fusarium oxysporum) retrotransposon
            skippy >gi|510697 (L34658) pol polyprotein [Fusarium
            oxysporum]
            Length = 1295
            
 Score = 47.3 bits (110), Expect = 2e-04
 Identities = 22/60 (36%), Positives = 36/60 (59%), Gaps = 1/60 (1%)

Query: 7    GEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILD-PRLLIAFQNRERQEQ 65
            G  V+  E+I   R   G+ EYL+KW+ +    NTWEP +++++  RLL  F  R R+++
Sbjct: 1232 GPEVYEAEAIRDTRKINGQREYLIKWKNYPENENTWEPPKHLVNAQRLLKDFHQRARKKE 1291

 sp|O14646|CHD1_HUMAN CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 (CHD-1) >gi|2645429
           (AF006513) CHD1 [Homo sapiens]
           Length = 1709
           
 Score = 46.9 bits (109), Expect = 3e-04
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 7/60 (11%)

Query: 18  KKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPK 77
           +K    G ++YL+KW+GWS  +NTWE EE +         QN    ++L  Y+K+  + K
Sbjct: 308 EKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQ-------QNVRGMKKLDNYKKKDQETK 360

 gi|3342716 (AF000981) testis-specific ChromoDomain Y isoform 1 [Homo
          sapiens]
          Length = 554
          
 Score = 46.1 bits (107), Expect = 6e-04
 Identities = 19/56 (33%), Positives = 38/56 (66%), Gaps = 1/56 (1%)

Query: 11 FAVESI-EKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQ 65
          F VE+I +K++ + G  +YLV+W+G+  + +TWEPE+++++    +   NR + E+
Sbjct: 6  FEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEK 61

 gi|3719261 (AF079405) heterochromatin-associated protein 1-like protein
          [Tetrahymena thermophila]
          Length = 184
          
 Score = 46.1 bits (107), Expect = 6e-04
 Identities = 20/51 (39%), Positives = 34/51 (66%)

Query: 10 VFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
          V+ VE+I   R +  ++EY ++W+G+S K  T+EP +NILD  +L  +Q +
Sbjct: 4  VYEVENIIGHRKKGSQIEYHIQWKGYSLKQATYEPAKNILDKNMLKKYQQK 54

 gi|2501846 (AF004397) chromo-helicase-DNA-binding on the Z chromosome protein
           [Gallus gallus]
           Length = 1808
           
 Score = 46.1 bits (107), Expect = 6e-04
 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 7/54 (12%)

Query: 24  GRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPK 77
           G ++YL+KW+GWS  +NTWE EE +         QN +   +L  Y+K+  + K
Sbjct: 311 GEIQYLIKWKGWSHIHNTWETEETLKQ-------QNVKGMNKLDNYKKKDQETK 357

 pir||A47392 chromodomain-helicase-DNA-binding protein, CHD-1 - mouse
           Length = 1711
           
 Score = 45.3 bits (105), Expect = 0.001
 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 7/54 (12%)

Query: 24  GRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPK 77
           G ++YL+KW+GWS  +NTWE EE +         QN    ++L  Y+K+  + K
Sbjct: 312 GDIQYLIKWKGWSHIHNTWETEETLKQ-------QNVRGMKKLDNYKKKDQETK 358

 sp|P40201|CHD1_MOUSE CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 (CHD-1) >gi|455015
           (L10410) DNA-binding protein [Mus musculus]
           Length = 1711
           
 Score = 45.3 bits (105), Expect = 0.001
 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 7/54 (12%)

Query: 24  GRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPK 77
           G ++YL+KW+GWS  +NTWE EE +         QN    ++L  Y+K+  + K
Sbjct: 312 GDIQYLIKWKGWSHIHNTWETEETLKQ-------QNVRGMKKLDNYKKKDQETK 358

 gi|2707217 (AF019969) Su(var)3-9 homolog [Mus musculus]
           Length = 412
           
 Score = 45.3 bits (105), Expect = 0.001
 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 21/119 (17%)

Query: 11  FAVESI-EKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGY 69
           F VE + + K+IR+    YLVKWRG+    NTWEP +N+   R+L  F +++ + +L+  
Sbjct: 43  FEVEYLCDYKKIREQEY-YLVKWRGYPDSENTWEPRQNLKCIRVLKQF-HKDLERELVRR 100

Query: 70  RKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELNSKKHH 128
            +R   P+ L           N+   L   +   RA          Q  + ELN+K+ H
Sbjct: 101 HRRSKPPRHL---------DPNLANYLVQKAKQRRAL---------QRWEQELNAKRSH 141

 gi|1397245 (U61944) coded for by C. elegans cDNA yk19a7.5; coded for by C.
          elegans cDNA yk45c10.5; coded for by C. elegans cDNA
          yk19a7.3; coded for by C. elegans cDNA yk45c10.3;
          contains similarity to CHROMO domains (PS:PS00598 and
          PS50013) [Caenorhabd...
          Length = 891
          
 Score = 44.9 bits (104), Expect = 0.001
 Identities = 22/53 (41%), Positives = 30/53 (56%)

Query: 8  EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
          E  F+  S+E  + R  +  YLV WRG+  K  TWEPEEN+ +   L  F+ R
Sbjct: 31 EAKFSPASVEYDKRRHSKYAYLVHWRGYDWKERTWEPEENLENCEELQKFKER 83

 gi|2707215 (AF019968) Su(var)3-9 homolog [Homo sapiens]
           Length = 412
           
 Score = 43.0 bits (99), Expect = 0.005
 Identities = 25/70 (35%), Positives = 41/70 (57%), Gaps = 3/70 (4%)

Query: 11  FAVESI-EKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGY 69
           F VE + + K+IR+    YLVKWRG+    +TWEP +N+   R+L  F +++ + +L+  
Sbjct: 43  FEVEYLCDYKKIREQEY-YLVKWRGYPDSESTWEPRQNLKCVRILKQF-HKDLERELLRR 100

Query: 70  RKRGPKPKPL 79
             R   P+ L
Sbjct: 101 HHRSKTPRHL 110

 sp|O14647|CHD2_HUMAN CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2 (CHD-2) >gi|2645431
           (AF006514) CHD2 [Homo sapiens]
           Length = 1739
           
 Score = 41.8 bits (96), Expect = 0.011
 Identities = 16/44 (36%), Positives = 31/44 (70%), Gaps = 2/44 (4%)

Query: 23  KGRVEYLVKWRGWSPKYNTWEPEENILDPRL--LIAFQNRERQE 64
           +G ++YL+KW+GWS  ++TWE EE++   ++  L   +N +++E
Sbjct: 302 EGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKE 345

 gi|818888 (U25814) chromodomain protein [Plasmodium falciparum]
          Length = 266
          
 Score = 41.4 bits (95), Expect = 0.014
 Identities = 17/39 (43%), Positives = 25/39 (63%)

Query: 11 FAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENIL 49
          F +  I + + +K    YLVKW+G+S   NTWEPE N++
Sbjct: 8  FEIGDILEIKKKKNGFIYLVKWKGYSDDENTWEPESNLI 46

 sp|Q10103|YAQ2_SCHPO HYPOTHETICAL 108.7 KD PROTEIN C18G6.02C IN CHROMOSOME I
          >gi|1122367|gnl|PID|e213851 (Z68198) putative
          heterochromatin protein [Schizosaccharomyces pombe]
          Length = 960
          
 Score = 40.6 bits (93), Expect = 0.025
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 10 VFAVESIEKKRIRKGRV-EYLVKWRGWSPKYNTWEPEENI 48
          V+ VE I   R+ K  + EY +KW G+    NTWEPE+N+
Sbjct: 21 VYEVEDILADRVNKNGINEYYIKWAGYDWYDNTWEPEQNL 60

 pir||S23571 hypothetical protein - fungus (Cladosporium fulvum) transposon
           CfT-1 >gi|2565 (Z11866) env homologue [Cladosporium
           fulvum]
           Length = 165
           
 Score = 39.9 bits (91), Expect = 0.042
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 8   EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILD-PRLLIAFQNRERQEQL 66
           E+ F VE I  K+ ++    YLVKW+G+    NTWEP  N+ +  +LL  FQ   +  + 
Sbjct: 85  ENEFEVEKILDKKGQR----YLVKWKGYDESENTWEPRINLANCYQLLRQFQKWRQDSRK 140

Query: 67  MGYRKRGPKP 76
              ++R   P
Sbjct: 141 QEAQERRASP 150

 sp|P40381|SWI6_SCHPO SWI6 PROTEIN >gi|510930 (X71783) swi6 gene product
           [Schizosaccharomyces pombe]
           Length = 328
           
 Score = 39.5 bits (90), Expect = 0.055
 Identities = 46/191 (24%), Positives = 74/191 (38%), Gaps = 28/191 (14%)

Query: 8   EHVFAVESIEKKRIRK--GRVEYLVKWRGW-SPKYNTWEPEENILDPRLLI-AFQNRERQ 63
           E  + VE + K R+ +  G  EYL+KW G+  P  NTW  E +    + LI A+ N    
Sbjct: 78  EDEYVVEKVLKHRMARKGGGYEYLLKWEGYDDPSDNTWSSEADCSGCKQLIEAYWNEHGG 137

Query: 64  EQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELN 123
                 RKR  +PK    + P+   R                K D     K    + E  
Sbjct: 138 RPEPSKRKRTARPKKPEAKEPSPKSR----------------KTDEDKHDKDSNEKIEDV 181

Query: 124 SKKHHQYQPHSKE--GKPRPPGKSGKYYYQLNSKKHHPYQ------PDPKMYDLQYQGGH 175
           ++K  ++   S+E   +  PP      + + +++   P Q       D ++ +       
Sbjct: 182 NEKTIKFADKSQEEFNENGPPSGQPNGHIESDNESKSPSQKESNESEDIQIAETPSNVTP 241

Query: 176 KEAPSPTCPDL 186
           K+ PSP  P L
Sbjct: 242 KKKPSPEVPKL 252

 gi|3510505 (AF030881) pol polyprotein [Fugu rubripes]
            Length = 1187
            
 Score = 39.1 bits (89), Expect = 0.072
 Identities = 20/54 (37%), Positives = 28/54 (51%)

Query: 7    GEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
            GE V++V  +   R R    +YLV W G+ P+  +W P   + DP LL  F  R
Sbjct: 1121 GEPVWSVNKLLAVRRRGRGFQYLVDWVGYGPEDQSWVPPSYLADPSLLEDFLPR 1174

 gi|538067 (M77661) putative pol polyprotein [Magnaporthe grisea]
            Length = 1398
            
 Score = 38.7 bits (88), Expect = 0.095
 Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 5/56 (8%)

Query: 8    EHVFAVESIEKKRIRKGRV---EYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 60
            E V+AVE+I   + R+GR    + LVKW+G+     TWEP E + D R L  F+ R
Sbjct: 1270 EEVWAVEAILAAKNRRGRGGGRQVLVKWQGYDNP--TWEPLELMTDTRALDEFEAR 1323

 gi|1448983 (L77907) chromodomain-helicase-DNA-binding protein [Drosophila
           melanogaster]
           Length = 1883
           
 Score = 38.3 bits (87), Expect = 0.12
 Identities = 17/55 (30%), Positives = 31/55 (55%), Gaps = 2/55 (3%)

Query: 27  EYLVKWRGWSPKYNTWEPEENILDPRL--LIAFQNRERQEQLMGYRKRGPKPKPL 79
           ++L+KW+GWS  +NTWE E  + D +   +    N  ++E+   Y +R   P+ +
Sbjct: 367 QFLIKWKGWSYIHNTWESEATLRDMKAKGMKKLDNFIKKEKEQAYWRRYAGPEDI 421

 gi|1519343 (U66363) Pdd1p [Tetrahymena thermophila] >gi|1519345 (U66364) Pdd1p
           [Tetrahymena thermophila]
           Length = 499
           
 Score = 38.3 bits (87), Expect = 0.12
 Identities = 33/141 (23%), Positives = 61/141 (42%), Gaps = 21/141 (14%)

Query: 8   EHVFAVESIEKKRI--RKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLI-AFQNRERQE 64
           E  + VE I   R   +  + EYLVKW  W  + +TWEP E++ + + ++ AF+ +++  
Sbjct: 46  EDQYEVEKILDSRFNPKTKQKEYLVKWENWPIEDSTWEPYEHLSNVKEIVQAFEKKQKAN 105

Query: 65  QLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELNS 124
            +       P+P   + +V             +D    NR  L+  +  K    + E+ +
Sbjct: 106 VM-------PQPTGPITRV----------NAQKDPQKKNRLSLN-SSISKSLPQEEEIQT 147

Query: 125 KKHHQYQPHSKEGKPRPPGKS 145
            K    +   K+ +P    KS
Sbjct: 148 SKEDSKKQAVKKFQPASRRKS 168

 gi|726375 (U23169) No definition line found [Caenorhabditis elegans]
           Length = 706
           
 Score = 37.9 bits (86), Expect = 0.16
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 15/92 (16%)

Query: 28  YLVKWRGWSPKYNTWEPEENILDPRLLIAFQ-------NRERQEQLMGY--RKRGPKPKP 78
           +LVKW G+  K  TWEPE NI D   L  ++       NR   +  + +  R++G  P  
Sbjct: 95  FLVKWLGYGNKEMTWEPESNIPDSVYLYEYKKLNNMVMNRMNLKVSLTFTSRRKGYTPPV 154

Query: 79  LVVQV------PTFARRSNVLTGLQDSSTDNR 104
           ++ ++      P F   SN+   L D+  + +
Sbjct: 155 ILEELQERKPKPQFLNMSNMAITLNDNLNNGK 186

 gnl|PID|e351430 (Z99568) elongation factor [Schizosaccharomyces pombe]
           Length = 1057
           
 Score = 37.5 bits (85), Expect = 0.21
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 3/66 (4%)

Query: 13  VESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILD---PRLLIAFQNRERQEQLMGY 69
           VE++  ++  K   +Y +KW G   KYNTW   E +L+    + + AF + E   + +G+
Sbjct: 822 VEALIGRQKLKKSFQYEIKWFGKPHKYNTWVSREILLENGFQKFVQAFDDMESSREGLGF 881

Query: 70  RKRGPK 75
           R+  P+
Sbjct: 882 RELIPE 887

 gnl|PID|e1332815 (AL031907) hypothetical protein [Schizosaccharomyces pombe]
           Length = 872
           
 Score = 36.4 bits (82), Expect = 0.48
 Identities = 17/60 (28%), Positives = 28/60 (46%)

Query: 10  VFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGY 69
           V  V     +R+   R++Y+  WR  +P Y       N +DP    AF+  E Q +++ Y
Sbjct: 154 VLTVLDCVSQRVEFARLDYIKVWRALAPIYRNLAYASNTIDPIAFSAFRTPEEQSKVLKY 213

 sp|P45975|SUV9_DROME SU(VAR)3-9 PROTEIN >gi|1079141|pir||S47004 Su(var)3-9 protein -
           fruit fly (Drosophila melanogaster) >gi|516328 (X80070)
           Su(var)3-9 [Drosophila melanogaster]
           Length = 635
           
 Score = 36.0 bits (81), Expect = 0.63
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 4   PAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQ 63
           P  GE+V  VE IE   + + +  + VKW G+    NTWE   N+ D   +  F  R +Q
Sbjct: 214 PPKGEYV--VERIECVEMDQYQPVFFVKWLGYHDSENTWESLANVADCAEMEKFVERHQQ 271


CPU time:     0.47 user secs.	    0.14 sys. secs	    0.61 total secs.

  Database: Non-redundant GenBank CDS
  translations+PDB+SwissProt+SPupdate+PIR
    Posted date:  Nov 22, 1998  9:28 PM
  Number of letters in database: 103,251,576
  Number of sequences in database:  338,166
  
Lambda     K      H
   0.312    0.132     0.00 

Gapped
Lambda     K      H
   0.270   0.0470 7.29e-304 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101262834
Number of Sequences: 338166
Number of extensions: 3972535
Number of successful extensions: 7458
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 7292
Number of HSP's gapped (non-prelim): 123
length of query: 558
length of database: 103251576
effective HSP length: 57
effective length of query: 501
effective length of database: 83976114
effective search space: 42072033114
effective search space used: 42072033114
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.8 bits)
S2: 71 (32.1 bits)