NCBI Conserved Domain Database
PubMed Nucleotide Protein Structure CDD Taxonomy Help?
CD: smart00067.10, GHA, Query added PSSM-Id: 59 Source: Smart
Description: Glycoprotein hormone alpha chain homologues. Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.
Taxa:  Euteleostomi References: 4 Pubmed Links Related: pfam00236
Status: Alignment from source Created: 12-Dec-2003
Aligned: 9 rows PSSM: 86 columns Representative: Consensus
Proteins: [Click here for CDART summary of Proteins containing smart00067]
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                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|
consensus    1 GCPECTLKENTIFSKPGA-PIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKE 59
query       40 ACGECSLGLNRLFSRDR--PLYQCMGCCFSRAYPTPQTAIQTMAIPKNITSEAKCCVAKH 97
1HRP_A       6 DCPECTLQENPFFSQPGA-PILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKS 64
gi 121306   33 GCEECKLKENNIFSKPGA-PVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKE 91
gi 121307   32 GCEECTLKPNTIFPN-----IMQCTGCCFSRAYPTPLRSKQTMLVPKNITSEATCCVAKE 86
gi 399546   33 GCEACTLRKNTVFSRDR--PIYQCMGCCFSRAYPTPLKAMKTMTIPKNITSEATCCVAKH 90
gi 121309   34 GCDECRLQENKIFSKPSA-PIFQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVARE 92
gi 1346138  40 ACGECSLGLNRLFSRDR--PLYQCMGCCFSRAYPTPQTAIQTMAIPKNITSEAKCCVAKH 97
gi 2851612  34 DCPECKLRENKYFFKLGV-PIYQCKGCCFSRAYPTPARSRKTMLVPKNITSESTCCVAKA 92
gi 121319   10 GCPECRLKENLRFSNMGIgRIYQCSGCCYSRAYPTPMRSKKTMLVPKNITSEAKCCVAKT 69

                       70        80
               ....*....|....*....|....*...
consensus   60 VYRV-VVDNIKVENHTDCHCSTCYYHKS 86
query       98 SYET-KVDDITVRNHTECHCSTCYYHKL 124
1HRP_A      65 YNRVtVMGGFKVENHTACHCSTCYYHKS 92
gi 121306   92 FKQV-LVNDIKLVNHTDCHCSTCYYHKS 118
gi 121307   87 GERVtTKDGFPVTNHTECHCSTCYYHKS 114
gi 399546   91 VYET-EVAGIRVRNHTDCHCSTCYYHKI 117
gi 121309   93 VTR---LDNMKLENHTDCHCSTCYYHKF 117
gi 1346138  98 SYET-KVDDITVRNHTECHCSTCYYHKL 124
gi 2851612  93 FIRVtVMGNIKLENHTQCYCSTCYHHKI 120
gi 121319   70 QYRVtVMDNVKIENHTACHCSTCLYHKS 97

Citing CDD: Marchler-Bauer A, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler GH, Mazumder R, Nikolskaya AN, Panchenko AR, Rao BS, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH (2003), "CDD: a curated Entrez database of conserved domain alignments", Nucleic Acids Res. 31: 383-387

 


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