CLUSTAL W (1.82) Multiple Sequence Alignments



Sequence format is Pearson
Sequence 1: MousePc3 gi|6707290      362 aa
Sequence 2: RatPc3 gi|27690850       366 aa
Sequence 3: HumanPc3 gi|9957028      389 aa
Sequence 4: ZebrafishPc3 gi|27374197     342 aa
Start of Pairwise alignments
Aligning...
Sequences (1:2) Aligned. Score:  96
Sequences (1:3) Aligned. Score:  93
Sequences (1:4) Aligned. Score:  44
Sequences (2:3) Aligned. Score:  93
Sequences (2:4) Aligned. Score:  43
Sequences (3:4) Aligned. Score:  47
Guide tree        file created:   [/ebi/extserv/old-work/479652.74688.dnd]
Start of Multiple Alignment
There are 3 groups
Aligning...
Group 1: Sequences:   2      Score:7682
Group 2: Sequences:   3      Score:7563
Group 3: Sequences:   4      Score:5180
Alignment Score 8882
CLUSTAL-Alignment file created  [/ebi/extserv/old-work/479652.74688.aln]

CLUSTAL W (1.82) multiple sequence alignment

                              Chromodomain

MousePc3          MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER 60
RatPc3            MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER 60
HumanPc3          MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER 60
ZebrafishPc3      MELSAVGERVFAAESIIKRRIRRGRMEYLVKWKGWSQKYSTWEPEENILDERLFAAFEER 60
                  **************:::*****:*************************** **:******

MousePc3          EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRA 120
RatPc3            EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRA 120
HumanPc3          EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA 120
ZebrafishPc3      EREREMYGPKKRGPKPETFLMKAKAKAKSKTYEFGREMSRDIRVSFPVAEP---VVTPRA 117
                  *** *:**********:***:**:****:*****  : :*.**:.:*  .*   . *.**

MousePc3          REGLRNTGLPPPGSSTST---CRADPPRDRDR------------------------ERDR 153
RatPc3            REGLRNTGLPPPGSSTST---CRADPPRDRDRDRDR--------------------ERDR 157
HumanPc3          REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER 180
ZebrafishPc3      REGLRTVVPTIFPPSTIN----RGESVRVRPPDS----------------------ERDT 151
                  *****.   .   .** .    *.:. * *                          **: 

MousePc3          GTSRVDDK-PSSPGDSSKKRGPKPRKEPLDPSQRPLGEPSAGLGEYLKGRKLDETSSGTG 212
RatPc3            GTSRVDEK-PSSPGDSSKKRGPKPRKELLDPSQRPLGEPSDGLGEYLKGRKLDETPSGIG 216
HumanPc3          GTSRVDDK-PSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAG 239
ZebrafishPc3      LTHGTSIQCPLDFANSPKKRGPKPK-------MHPAGGSSS---EGIK-RKADESLS--- 197
                   *  .. : * . .:*.*******:        :* * .*    * :* ** *:: *   

MousePc3          KFPAGHSVIQLARRQDSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEAKGQGA 272
RatPc3            KFSAGHSVIQLARRQDSDLVQYGVTSPSSAEASGKLAADTFPARVIKHRAALLEAKGQGA 276
HumanPc3          KFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGA 299
ZebrafishPc3      -YRP-SKTERSGETSNCDIMHFTQKYKAETTHDGKQMGSRSSDVKFSHGGSFLKA-GLGI 254
                   : .  .. : .. .:.*:::   .  :.:   .*   .  .   :.* .::*:* * * 

MousePc3          LDPGGARVRHSSGTPASVGSLYRDMGAQGG-RPSLIARIPVARILGDPEEESWSPSLTNL 331
RatPc3            LDPGGTRVRHSSGTPGSVGSLYRDMGAQGG-RPSLIARIPVARILGDPEEESWSPSLTNL 335
HumanPc3          LDPNGTRVRHGSGPPSSGGGLYRDMGAQGG-RPSLIARIPVARILGDPEEESWSPSLTNL 358
ZebrafishPc3      L---GHRQKVGSGGAINQQAKMKHPPKNNLYRSTDQTREQLSLSFVDDTDQSWLPCLKNM 311
                  *   * * : .** . .  .  :.   :.  *.:  :*  ::  : *  ::** *.*.*:

MousePc3          EKVVVTDVTSNFLTVTIKESNTDQGFFKEKR 362
RatPc3            EKVVVTDVTSNFLTVTIKESNTDQGFFKEKR 366
HumanPc3          EKVVVTDVTSNFLTVTIKESNTDQGFFKEKR 389
ZebrafishPc3      EKIVVTDVTSNSLTVTIKESSTDKGFFKENR 342
                  **:******** ********.**:*****:*
                       COOH-Box

(
(
MousePc3:0.01321,
RatPc3:0.01717)
:0.03033,
HumanPc3:0.01628,
ZebrafishPc3:0.51296);