Folder: ZebrafishPolycombAlignment

File: Clustalw_Alignment_Zebrafish_Polycomb1_2_3_Proteins

 CLUSTAL W (1.82) Multiple Sequence Alignments

Sequence format is Pearson
Sequence 1: ZebrafishPc1      510 aa
Sequence 2: ZebrafishPc2      477 aa
Sequence 3: ZebrafishPc3      343 aa
Start of Pairwise alignments
Aligning...
Sequences (1:2) Aligned. Score:  17
Sequences (1:3) Aligned. Score:  26
Sequences (2:3) Aligned. Score:  25
Guide tree        file created:   [/ebi/extserv/old-work/999792.975631.dnd]
Start of Multiple Alignment
There are 2 groups
Aligning...
Group 1:                     Delayed
Group 2:                     Delayed
Sequence:3     Score:3646
Sequence:2     Score:3101
Alignment Score 948
CLUSTAL-Alignment file created  [/ebi/extserv/old-work/999792.975631.aln]

Folder: ZebrafishPolycombAlignment

File: Clustalw_Alignment_Zebrafish_Polycomb1_2_3_Proteins

CLUSTAL W (1.82) multiple sequence alignment

                                   Chromodomain

ZebrafishPc1      MEELSAVGEQVFDAECILNKRTRKGKLEYLVKWRGWSSKHNSWEPQENLLDPRLLVAFNK 60
ZebrafishPc3      -MELSAVGERVFAAESIIKRRIRRGRMEYLVKWKGWSQKYSTWEPEENILDERLFAAFEE 59
ZebrafishPc2      -MELPAVGEHVFAVEGIEKKRLRKGRMEYLVKWRGWSPKYNTWEPEENILDPRLLVAFQN 59
                    **.****:** .* * ::* *:*::******:*** *:.:***:**:** **:.**::

ZebrafishPc1      REQEKELLISKKGKRPRGRPRKIMETIPVVSKSSSSSSSSSSSGSSSSSSSSSSSTDDDD 120
ZebrafishPc3      REREREMYGPKKRG---------------------------------------------- 73
ZebrafishPc2      RERQEQMVGYRKRGPKPKHPLIQLPAFARRSSILGG--------------LQDTSLDEEN 105
                  **::.::   :*                                                

ZebrafishPc1      EDDHNMTPKPIPRPREHLPVPQKKAQIVVAKPGPPKKRGRKALPPELKAIRQVKGTRKIL 180
ZebrafishPc3      -----------PKPETFLMKAKAKAKSKTYEFGREMSRDIRVSFPVAEPVVTPRAR---- 118
ZebrafishPc2      QPKVDSLQMHRSRPQHYQLNSKKHHQYQPSCKEISVEQHMSGKKKHFYQLNSKKHHHYQ- 164
                             .:*. .   .: : :          .:           :   :      

ZebrafishPc1      KPISRDSDLRGIKKPLMPASFTYTGLNRTSGREPMAMHNRGSFTHKSSLSSLGRSIGSVS 240
ZebrafishPc3      ------EGLRTVVPTIFPPSTINRGE---SVRVRPPDSERDTLTHG----------TSIQ 159
ZebrafishPc2      ------PDPKMYDTPLTGPKEVKGQDPSNKGWNLPPALQQKWIRNKDTGCLSKVKDLSIE 218
                         . :    .:  ..         .     .  ::  : :            *:.

ZebrafishPc1      SPPTLNRSPQTKSASDFKLSVSDMNSGLDPKTPTCKSPGVAALNLHSSNGQTCPQLSPTV 300
ZebrafishPc3      CPLDFANSPKKR----------------GPKPKMHPAGGSSSEGIKR------------- 190
ZebrafishPc2      LKGLPDNANKAERTLKTSAKEFALPNGISSKMKIIKNKNKNGRIVIVMSKYMDKGVHSSK 278
                        .: : .                ..*       .  .  :               

ZebrafishPc1      PKDQTLLQRSASLPKSPSSSFSSLKTPSSLQALNLQSVNKTVQGNGTDLKTSPHSGRKSS 360
ZebrafishPc3      KADESLSYRPSKTERSGETSNCDIMHFTQKYKAETTHDGKQMGSRSSDVKFSHGGSFLKA 250
ZebrafishPc2      VKNRDVSQVGTVHNEEPPVNGTDNRSDGETPDQGEGRENGSIEKPSEYVDEKSLRKDMPG 338
                    :. :    :   ..   .  .     .         .  :   .  :. .       .

ZebrafishPc1      GFNTSSAPNTPSKFQTSQQALKSPQKLKADDLAERLGKKSQARTEKILPTEGRDSQPAQD 420
ZebrafishPc3      GLG-------------------------------ILGHRQKVGSGGAINQQAKMKHPPKN 279
ZebrafishPc2      QKATEICDRPNSSPAKVDAKSNHLKRHLSEPSEDVRNCKQLLSFRSISAPNSSPQREPIN 398
                                                      . :.          :.  .: . :

ZebrafishPc1      RPSSKDPSKQSKTLSELSTGEEGSSSDTDHDSSFPRDSHDLSISVQAGQDWRPTRSLIEH 480
ZebrafishPc3      --------------------------NLYRSTDQTREQLSLSFVDDTDQSWLPCLKNMEK 313
ZebrafishPc2      LHYKSSPVDNYDFSDSIP--EEPIDLSAKTLKRFTALDKVSGSSAQMDKTDSQCKAFVGN 456
                                            .    .  .  .   .   : .:        : :

ZebrafishPc1      VFVTDVTANLVTVTVKESPTSVGFFSIRNY 510
ZebrafishPc3      IVVTDVTSNSLTVTIKESSTDKGFFKENR- 342
ZebrafishPc2      VIITDITTNCLTVTFKEYVQE--------- 477
                  :.:**:*:* :***.**   .         
                       COOH-Box

(
ZebrafishPc1:0.40717,
ZebrafishPc2:0.41883,
ZebrafishPc3:0.32461);