Endocrine Disruptor: This Webpage was compiled by Dr. Lin at The Hormone Research Center (HRC), Korea in the summer of 2004 under the sponsorship of the NIH-MIRT program. Dr. Lin would like to thank Dr. H-B Kwon (Director, HRC), Dr. R-S Ahn, faculty and staffs at the HRC for their input and hospitality
NRDC: Endocrine Disruptors FAQ
An endocrine disruptor is a synthetic chemical that when absorbed into the body either mimics or blocks hormones and disrupts the body's normal functions. This disruption can happen through altering normal hormone levels, halting or stimulating the production of hormones, or changing the way hormones travel through the body, thus affecting the functions that these hormones control. Chemicals that are known human endocrine disruptors include diethylstilbesterol (the drug DES), dioxin, PCBs, DDT, and some other pesticides. Many chemicals, particularly pesticides and plasticizers, are suspected endocrine disruptors based on limited animal studies.
© Natural Resources Defense Council
http://www.nrdc.org/health/effects/qendoc.asp
Endocrine Disruptor Screening Program In recent years, some scientists have proposed that certain chemicals might be disrupting the endocrine system of humans and wildlife. A variety of chemicals have been found to disrupt the endocrine systems of animals in laboratory studies, and compelling evidence shows that endocrine systems of certain fish and wildlife have been affected by chemical contaminants, resulting in developmental and reproductive problems. Based on this and other evidence, Congress passed the Food Quality Protection Act in 1996, requiring that EPA initiate EDSP to screen pesticide chemicals and environmental contaminants for their potential to affect the endocrine systems of humans and wildlife.
http://www.epa.gov/scipoly/oscpendo/
[Endocrine-Disrupting Chemicals, EDC] (Google)
What are Endocrine Disruptors?
PAUL GOETTLICH 16jun01 (rev.5dec03)
[More
by Paul Goettlich]
RiskWorld’s Index
Food and Drug Administration (FDA)
Endocrine Disruptor Knowledge Base [EDKB]
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EHP: Environmental Health Perspectives (Endocrine Disruptor)
Endocrine
Disruptors - NIEHS Alphabetical Listing of Health Topics
Answers to some common environmental
questions from NIEHS, the National Institute of Environmental Health
Sciences, which conducts basic research on ..
http://www.niehs.nih.gov/external/faq/endisrp.htm
- 7.8KB
Environews Topic:
Endocrine Disruptors
| Colborn T, vom Saal FS, Soto AM. | Related Articles | |
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Developmental effects of endocrine-disrupting chemicals
in wildlife and humans. Environ Health Perspect. 1993 Oct;101(5):378-84. Review. [FullText] |
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| Colborn T. | Related Articles | |
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Neurodevelopment and endocrine
disruption. Environ Health Perspect. 2004 Jun;112(9):944-9. Review. [pdf] |
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| DeVito M, Biegel L, Brouwer A, Brown S, Brucker-Davis F, Cheek AO, Christensen R, Colborn T, Cooke P, Crissman J, Crofton K, Doerge D, Gray E, Hauser P, Hurley P, Kohn M, Lazar J, McMaster S, McClain M, McConnell E, Meier C, Miller R, Tietge J, Tyl R. | Related Articles | |
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Screening methods for thyroid
hormone disruptors. Environ Health Perspect. 1999 May;107(5):407-15. Review. [FullText] |
|
| Colborn T. | Related Articles, | |
|
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Clues from wildlife to create an
assay for thyroid system disruption. Environ Health Perspect. 2002 Jun;110 Suppl 3:363-7. Review. [FullText] [pdf] |
|
Exposure to 4-tert-Octylphenol Accelerates Sexual Differentiation and Disrupts Expression of Steroidogenic Factor 1 in Developing Bullfrogs (pdf), Environmental Health Perspectives • VOLUME 111 | NUMBER 4 | April 2003; Loretta P. Mayer, Cheryl A. Dyer, and Catherine R. Propper; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA
Chemical communication threatened by endocrine-disrupting
chemicals. Fox JE. Environmental Endocrinology
Laboratory, Center for Bioenvironmental Research at Tulane and Xavier
Universities, New Orleans, Louisiana, USA.
jenfox@uoregon.edu. Environ Health Perspect.
2004 May;112(6):648-53.
[pdf]
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In Vitro Endocrine Disruptor Screening Assays (NIEHS)
BACKGROUND REVIEW MATERIALS
|
Endocrine Disruptor BRD Page (Final)
NIEHS Press Release - Reports in Children’s Environmental Health Issue Suggest:
Maternal ...
Data collected in eight geographic
areas in North America, Europe, and Israel suggest that maternal vitamin
supplementation for two ..
http://www.niehs.nih.gov/oc/news/chealth.htm
- 10.3KB
 | ICCVAM Evaluation of In Vitro Test Methods For Detecting Potential Endocrine Disruptors: |
| Estrogen Receptor and Androgen Receptor Binding and Transcriptional
Activation Assays. NIH Publication No. 03-4503. May 2003. [PDF (8.4 MB) or HTML] |
Cloning and characterization of estrogen
receptor alpha in mummichog, Fundulus heteroclitus. Urushitani H,
Nakai M, Inanaga H, Shimohigashi Y, Shimizu A, Katsu Y, Iguchi T. Mol Cell
Endocrinol. 2003 May 30;203(1-2):41-50. [HTML
or
PDF]
doi:10.1016/S0303-7207(03)00118-7 
Copyright © 2003 Elsevier Science Ireland Ltd. All rights reserved.
Interaction of xenobiotics with estrogen receptors alpha and
beta and a putative plasma sex hormone-binding globulin from channel catfish (Ictalurus
punctatus) •
ARTICLE
General and Comparative Endocrinology, Volume 136, Issue 3,
William L. Gale , Reynaldo Patińo and Alec G. Maule (pdf)
SummaryPlus |
Full Text + Links |
PDF (231 K)
Laboratory of Reproductive and Developmental Toxicology (NIHES)
Laboratory of Signal Transduction (LST)
Laboratory of Computational Biology and Risk Analysis (LCBRA)
The
National Toxicology Program (NTP)
Center for the Evaluation of
Risks to
Human Reproduction
(CERHR)
National Toxicology Program Center for the Evaluation of Risks to
Human
Reproduction (CERHR) - http://cerhr.niehs.nih.gov/
Resource for the latest information about potentially hazardous
effects of chemicals on human reproduction and development.
Endocrine and Metabolic Diseases - http://www.niddk.nih.gov/health/endo/endo.htm
Patient information on a variety of endocrine disorders.
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NIH Search Results
|
Advanced Search |
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|
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Searched for NIH Guide SUPERFUND BASIC RESEARCH AND TRAINING PROGRAM.
NIH
Guide: SUPERFUND BASIC RESEARCH AND TRAINING PROGRAM
SUPERFUND BASIC RESEARCH AND TRAINING
PROGRAM RELEASE
DATE: August 27, 2004 RFA Number: RFA ...
grants2.nih.gov/grants/guide/rfa-files/RFA-ES-05-001.html
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Cached
The Superfund Basic Research Program is focused on acquiring new scientific and engineering knowledge that advances both society's understanding of the human and ecological risks from hazardous substances and the development of new environmental technologies for the cleanup of Superfund sites.
2004 RESEARCH BRIEFS |
Research Brief 116: Investigating the Impact of Organic Mixtures on Cardiac Development of the Killifish (Release Date: 08/04/2004) |
| (Superfund
Chemicals Impact on Reproduction and Development,
Duke Univ.-
P42ES10356)
Markers for Chemical Mixtures in Fundulus heteroclitus
Transgenic Fish as Biosensors for Superfund Chemicals |
1998 RESEARCH BRIEFS |
Research Brief 21: Mechanisms of Dioxin Sensitivity and Acquired Resistance (Release Date: 05/27/1998) |
| (Superfund Basic Research Center at Boston University- P42ES07381) |
Office of Research and Development (ORD)
Endocrine Disruptor Research Initiative (Fact Sheet, Publications)
Endocrine Disruptor Screening Program (EDSP)
The Health and Ecological Effects of Endocrine Disrupting Chemicals: A Framework for Planning (PDF), (research inventory)
Assay Development and Validation
Priority Setting Activities
![[PDF] Endocrine Disruptor Screening Proposed Chemical Selection Approach](images/ik_pdf.gif){kind=small}
Framework for the Global Endocrine Disruptor Inventory
The research planning framework used to develop this
inventory was patterned after that developed by the Endocrine
Disruptor Working Group of the US Committee on the Environment and
Natural Resources and which is included in the document entitled "The
Health and Ecological Effects of Endocrine Disrupting Chemicals: A
Framework for Planning."
Polychlorinated Biphenyls (PCBs)
PCB Home Page at EPA - http://www.epa.gov/opptintr/pcb/
Provides information on Polychlorinated Biphenyls
(PCB's). Background, resources and links to many topics.
Health Effects of PCBs; EPA (PCBs) Information Resources
EPA Superfund
| Summary of the 2002 National Forum on Contaminants in Fish |
|
Chemical-specific Fact Sheets
Information on PCBs, Toxaphene, Mercury, and Polychlorinated Dibenzo-p-dioxins |
| Exposure to Polychlorinated Biphenyls (PCBs) -- Public Health Implications of Exposure to PCBs |
| Database: National Survey -- Survey of Mercury Concentrations in Fish (1990-1995) |
| Proceedings from the National Risk Communication Conference |
| Summary of the 2001 National Forum on Contaminants in Fish Chicago, May 6 & 9, 2001 |
EPA Search Results
EPA
Browse Pages for endocrine disruptor
 |
| Pollutants/Toxics -> Chemicals -> Endocrine Disruptors |
| Rank | Title & Summary | Format |
|---|---|---|
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| 11 |
Endocrine Disruptors and Testis Development
The proposed research is designed to develop a better understanding of how endocrine disruptors influence testis development and function. URL: http://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstr actDetail/abstract/992 |
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| 12 |
Development and Preliminary Validation of a Rapid
Progestin-Based Endocrine Disruption Screening Assay (Final
Report)
Xenopus
laevis oocyte maturation germinal vesicle breakdown (GVBD) model as
a system for the rapid evaluation of endocrine-disrupting chemicals (EDCs)
found in the workplace or the environment.
Concerns regarding the presence of endocrine disruptors in food, water, or other environmental media as well as concerns about the potential risk they pose to humans and wildlife have been growing in recent years. URL: http://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstr actDetail/abstract/5079 |
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| 56 |
Potential of Chemicals to Affect the Endocrine System
Discusses endocrine disruptors, their effects, and what steps the EPA is taking to address the issue. URL: http://www.epa.gov/pesticides/factsheets/3file.htm |
The
National Institute of Occupational Safety and
Health (NIOSH)
- The National
Institute for Occupational Safety and Health (NIOSH) is the Federal agency
responsible
for conducting research and making recommendations for the prevention of
work-related
disease and injury. The Institute is part of the Centers for Disease Control and
Prevention (CDC). NIOSH has a variety of publications on PCBs. To locate these
documents, enter PCBs or Polychlorinated Biphenyls or PCB in NIOSH's search
function
The Occupational Health and Safety Administration (OSHA) - The mission of the Occupational Safety and Health Administration (OSHA) is to save lives, prevent injuries and protect the health of America's workers. To accomplish this, federal and state governments must work in partnership with the more than 100 million working men and women and their six and a half million employers who are covered by the Occupational Safety and Health Act of 1970. OSHA has a variety of publications on PCBs. To locate these documents, enter PCBs or Polychlorinated Biphenyls or PCB in OSHA's search function.
The Agency for Toxic Substances and Disease Registry
(ATSDR) -
The mission of the
Agency for Toxic Substances and Disease Registry (ATSDR), as an agency of the US
Department of Health and Human Services, is to prevent exposure and adverse
human
health effects and diminished quality of life associated with exposure to
hazardous substances from waste sites, unplanned releases, and other sources of
pollution present in the environment
The public health implications of polychlorinated biphenyls (PCBs) in the environment • REVIEW ARTICLE
Volume 59, Issue
3, Pages 275-376 (November 2004)
Gilbert Ross
American Council
on Science and Health, 1995 Broadway, 2nd Floor, New York, NY 10023-5860,
USA
SummaryPlus |
Full Text + Links
|
PDF (328 K)
American Council on Science and Health -
Disinfopedia
American Council on Science and Health.
... American Council on Science and Health
1995
Broadway New York, NY 10023-5860 phone: (212) 362-7044 http://www.acsh.org.
...
www.disinfopedia.org/wiki.phtml?title=American_
Council_on_Science_and_Health - 44k
Introduction
This site provides interactive access to data from NASS, as part of a
cooperative effort among USDA, the USDA Regional Pest Management
Centers and the NSF Center for Integrated Pest Management (CIPM). All
data available have been previously published by NASS and have been
consolidated at the state level.
NSFCIPM fosters the development and implementation of pest management programs based on a high level of knowledge of pest biology coupled with choices of monitoring tools and control technology, resulting in economically sound, environmentally compatible, and sociologically responsible integrated crop production
Advanced Search [endocrine] [endocrine disruption]
| 1. | ARS | Publication request: Relationship Between Fatty Acids and the Endocrine System. ARS | | |
| ...Department of Agriculture (USDA) Agricultural Research Service (ARS) Agricultural Research...Between Fatty Acids and the Endocrine System. Author item Bhathena...dietary fatty acids and the endocrine system. In turn, endocrine system (hormones) also... | ||
| http://iapreview.ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=108571&pf=1 | ||
| 2. | ARS | Publication request: Endocrine Responses to Short-Term Feed Deprivation in Weanling Pigs ARS | ||||||||||||
| ...Department of Agriculture (USDA) Agricultural Research Service (ARS) Agricultural Research...Service Research > Title: Endocrine Responses to Short...objective was to determine endocrine responses to a short-term...Site Map - Contact Us - Freedom of Information... | |||||||||||||
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Endocrine Disruption in Fish:
An Assessment of Recent Research and Results
U.S. Department of Commerce, (NOAA) National Oceanic and Atmospheric Administration
NOAA Technical Memorandum NOS NCCOS CCMA 149 (html)
Center for Coastal Monitoring and Assessment (CCMA), National Centers for Coastal Ocean Science (NCCOS), National Ocean Service (NOS)
Pait, A.S. and J. O. Nelson. 2002. Endocrine Disruption in Fish: An Assessment of Recent Research and Results. NOAA Tech. Memo. NOS NCCOS CCMA 149. Silver Spring, MD: NOAA, NOS, Center for Coastal Monitoring and Assessment 55pp.
The National Marine Fisheries Service (NOAA Fisheries) dedicated to the stewardship of living marine resources through science-based conservation and management, and the promotion of healthy ecosystems.
National Environmental Policy Act Overview
The Southeast Fisheries Science Center conducts multi-disciplinary research programs to provide management information to support national and regional programs of NMFS; and to respond to the needs of Regional Fishery Management Councils, Interstate and International Fishery Commission, Fishery Development Foundations, government agencies, and the general public.
OUR LIVING OCEANS
REPORT ON THE STATUS OF U.S. LIVING MARINE RESOURCES 1999
(pdf)
NMFS. 1999. Our Living Oceans. Report on the status of U.S. living marine resources, 1999. U.S. Dep. Commer., NOAA Tech. Memo. NMFS-F/SPO-41, on-line version, http://spo.nwr.noaa.gov/olo99.htm.
Recognizing the importance of fish habitat to the productivity and sustainability of U.S. marine fisheries, in 1996 Congress added new habitat conservation provisions to the Magnuson-Stevens Fishery Conservation and Management Act (Magnuson-Stevens Act), the federal law that governs U.S. marine fisheries management. Congress asserted the following in the Findings section of the Magnuson-Stevens Act:
One of the greatest long-term threats to the viability of commercial and recreational fisheries is the continuing loss of marine, estuarine, and other aquatic habitats. Habitat considerations should receive increased attention for the conservation and management of fishery resources of the United States (16 U.S.C. 1801 (A)(9)).
A Bouillabaisse of
Fascinating Facts About Fish
These are the Most Frequently Asked Questions containing some fascinating facts about fish
Contaminants in the Environment
|
Contaminants
can impact natural resources, public health and the economy. Most enter the
environment from industrial and commercial facilities; oil and chemical
spills; non-point sources such as roads, parking lots, and storm drains; and
wastewater treatment plants and sewage systems. Many hazardous waste sites and
industrial facilities have been contaminated for decades and continue to impact
the environment.
Pollutants that resist breakdown and accumulate in the food chain
are of greatest concern because they are consumed or absorbed by fish and
wildlife, which in turn are consumed by humans. The chemical contamination of
sediments continues to affect large coastal areas, threaten human health, and
reduce the economic well-being of regions that depend on a healthy
coastal environment.
NOAA acts as a trustee for coastal and marine resources under the authority of the Clean Water Act, the Comprehensive Environmental Response, Compensation and Liability Act of 1990, the National Marine Sanctuaries Act, the Coastal Zone Management Act, and the Oil Pollution Act of 1990. In addition, the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) identifies the Department of Commerce as the primary federal trustee for protecting and restoring coastal resources affected by oil or hazardous materials. The NCP also describes NOAA’s role in providing scientific support during response activities and participating in domestic and international planning and response activities
Contamination can lead to detrimental effects in fish and other species. Shown here is a fish with tumors
Office of Ocean and Coastal Resource Management
Florida Everglades Restoration Plan
Click here to read more about the plan.
The Central and Southern Florida Project Comprehensive
Plan provides the road map for restoring and protecting the south Florida
ecosystem. The Plan "gets the water right" by addressing four fundamental
issues: the quantity, quality, timing and distribution of water.
The Comprehensive Plan is also part of a larger effort to restore the ecosystem and provide for a sustainable south Florida. A strategic plan for this larger effort is being developed under the direction of the South Florida Ecosystem Task Force by federal, state, local and tribal leaders. It will focus on bringing together other restoration efforts under one framework. Over 200 projects will be tied together under the strategic plan.
The Comprehensive Everglades Restoration Plan (CERP)
Welcome to the U.S. Geological Survey
Federal source for science about the
Earth, its natural and
living resources, natural hazards, and the environment.
SOFIA - Paper - The Role of
Flow in the Everglades Ridge and
...
... are two main purposes of this paper:
1) to increase awareness among scientists and
resource managers of the importance of flow to Everglades
restoration, and 2 ...
sflwww.er.usgs.gov/publications/ papers/sct_flows/background.html
- 20k -
SOFIA - Project Summary
... Overview & Objective(s): A
foundation for the Everglade's restoration must include
a clear understanding of the pre-drainage south Florida landscape.
...
sflwww.er.usgs.gov/projects/ summary_sheets03/digarchive.html
- 22k -
Welcome to the USGS Contaminant Biology Program
The USGS Contaminant Biology Program investigates the effects and exposure of environmental contaminants to the Nation's living resources, particularly those under the stewardship of the Department of the Interior
Fisheries: Aquatic and Endangered Resources Program
Research of the Fisheries: Aquatic and Endangered Resources Program is focused on the study of fishes, fisheries, aquatic invertebrates, and aquatic habitats. Systematic research evaluates factors that affect aquatic organism health, population fitness, biological diversity, and aquatic community and habitat function
USGS Terrestrial, Freshwater, and Marine Ecosystems Program
- DOI Science Plan in Support of Ecosystem Restoration, Preservation, and Protection in South Florida (published in May 2004) [Executive Summary] [ Water]
The South Florida Water Management District (SFWMD)
Does
Everglades Restoration
Mean More Florida Bay Mercury?
09/03 (NCCOS
Monthly Feature Story)
FDA - Mercury Levels in Commercial Fish
and Shellfish
... Service Survey of Trace Elements in the
Fishery Resource" Report 1978 "The Occurrence of Mercury
in the Fishery Resources of the Gulf of Mexico"
Report 2000. ...
2003 Everglades Consolidated Report
Mercury Monitoring, Research and Environmental Assessment (pdf)
A Survey of Mercury in the Fishery Resources of the Gulf of Mexico (A9.com Search)
Mercury
Forum
... biography. Dr. Kopfler's abstract. Dr. Kopfler's PPT
presentation. Survey of the Occurrence of Mercury in Fishery
Resources of the Gulf of Mexico Dr. Frederick ...
http:/
National Listing of Fish Advisories (Advisories, Listing, Fact Sheet)
Gulf of Mexico Program (EPA)
Mercury Research in the
USGS
Improved information on mercury sources, cycling and toxicity will help land and resource managers understand what can be done to reduce mercury hazards to people and the environment. The large geographic scope and consequences of mercury contamination, and enormous complexity of the problem require a scientific approach that integrates many scientific disciplines. USGS investigations provide information to guide environmental planning and management. This information helps managers reduce mercury contamination of our biological resources and the associated threats to humans and wildlife.
Mercury in the Environment [Factsheet]
Mercury Contamination of Aquatic Ecosystems [html] [pdf]
Fish Advisories Nationwide [map] [database]
Mercury Roundtable [about]
| USGS Programs that Support Mercury Science |
| Information from Other Agencies |
| Mercury Related EPA Websites |
Toxicological Effects of Methylmercury [pdf]
METHYLMERCURY IN THE GULF OF MEXICO: STATE OF KNOWLEDGE
AND
...
... in the Gulf of Mexico: NOAA Fisheries’
Synoptic Survey Estuarine Sampling ... generated a report “The
Occurrence of Mercury in the Fishery Resources of the
...
http:/
METHYLMERCURY IN THE GULF OF MEXICO:
STATE OF KNOWLEDGE AND RESEARCH NEEDS
Report of the
NATIONAL SCIENCE AND TECHNOLOGY COUNCIL (NSTC)
COMMITTEE ON THE ENVIRONMENT AND NATURAL RESOURCES
Interagency Working Group on Methylmercury
June 2004
The vision of the Service and its Fisheries Program is working with partners to restore and maintain fish and other aquatic resources at self-sustaining levels and to support Federal mitigation programs for the benefit of the American public.
Amphibian Declines & Deformities
Fact Sheet on Amphibian Deformities and Refuges (pdf file)
Endocrine
(hormone) Disruptors
Habitat
Restoration
Superfund
Oil
Spills
National Institute of Health Sciences (Japan)
Estrogen Receptor
Endocrine Disruptor Information for Researchers, Japan (NIHS)
Information
and Computing Infrastructure for Endocrine Disruptors
... The main components of this database
complex are a potential endocrine disruptor
database, a receptor database, a cell signaling network database, a ...
www.nihs.go.jp/hse/endocrine-e/paper/1999-1.html
- 30k
Endocrine disruptors Canada
CCOHS:
Features: Assessing the Risk and Extent of Endocrine ...
... Potential endocrine disruptor
substances identified by organizations such as the
US Environmental Protection Agency and Japan’s Environment Agency
are ...
www.ccohs.ca/headlines/text69.html - 24k
Endocrine Disrupting Substances in the Environment (html)
Endocrine Disruptor Research in the European Union
Organisation for Economic Co-operation and Development (OECD)
Endocrine Disrupter Testing and Assessment
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Persistent Organic Pollutants (POPs) - http://www.chem.unep.ch/pops/
These chemical substances persist in the environment,
bioaccumulate through the food web, and pose a risk of causing adverse effects
to human health and the environment. From the United Nations Environment
Programme (UNEP).
World Wildlife Fund (WWF)
WWF Endocrine Disruptor Information
© 2001-2004 WWF.
WWF's Living Planet Report (2004) [pdf]
WWF
| Toxic Chemicals | Conservation Results
... Wildlife researchers over the last
several years have unearthed a variety of endocrine
disruptor-related effects: interrupted sexual development;
thyroid ...
www.worldwildlife.org/toxics/results/results2.cfm
- 35k
The Global Footprint Network is committed to fostering a world where all people have the opportunity to live satisfying lives within the means of Earth's ecological capacity. We are dedicated to advancing the scientific rigor and practical application of the Ecological Footprint, a tool that quantifies human demand on nature, and nature's capacity to meet these demands. Created in 1993 by Mathis Wackernagel and William Rees, the Ecological Footprint is now in wide use by governments, communities, and businesses to monitor current ecological resource balances and to plan for the future.
Environmental Defense (ED) is fighting to protect human health, restore our oceans and ecosystems, and curb global warming.
Questions about Endocrine Disruptors
Bergeson
& Campbell, PC -- Endocrine Disruptors
Bergeson & Campbell, PC provides frequent
memoranda on endocrine issues such as
the Endocrine Disruptor Screening Program (EDSP),
EPA’s strategy for ...
www.lawbc.com/endocrine.shtml - 14k -
e.hormone
| hormones and the environment
... Endocrine Disrupting
Chemicals Estrogens Explainer Estrogens and Estrogen-mimicking
Compounds Featured Definition: Endocrine Disruption. News and
Views. ...
e.hormone.tulane.edu/ - 18k - Sep 7, 2004 -
The Center for Community Action and Environmental Justice
Environmental Research Foundation
Rachel's Environment & Health News
NRDC:
Endocrine Disruptors FAQ
... 2. What is an endocrine disruptor?
An endocrine ... 7. Are children at greater risk
from endocrine disruptor exposure? Yes. Because endocrine
...
www.nrdc.org/health/effects/qendoc.asp - 25k -
Sep 8, 2004
New Studies Confirm Dangers of Atrazine, a Widely Used Agricultural
Weed-Killer - http://www.nrdc.org/health/pesticides/natrazine.asp
NRDC website describes research suggesting the
atrazine is a carcinogen and causes sexual abnormalities in male
frogs.
.NRDC: The
Story of Silent Spring
... Kennedy ordered the
President's Science Advisory Committee to examine the issues
the book raised, its report thoroughly vindicated both Silent
Spring and its ...
www.nrdc.org/health/pesticides/hcarson.asp - 25k
- Oct 4, 2004
A Science Odyssey: People and Discoveries: "Silent Spring" is ...
... Until her friend's letter arrived.
Carson spent much of 1958 to 1962 researching
and writing the book that would be Silent Spring.
...
www.pbs.org/wgbh/aso/databank/entries/dt62si.html
Frontline:
fooling with nature: special reports: silent spring ...
... coast -- indeed gone the way of the
passenger pigeon, whose flocks once darkened
the afternoon sky -- had it not been for a book (Silent
Spring) that forever ...
www.pbs.org/wgbh/pages/frontline/
shows/nature/disrupt/sspring.html
Copyright © 1996-2004 RachelCarson.org ® All Rights Reserved
www.rachelcarson.org
a website devoted to the life and legacy of Rachel Carson
An Overview of the Endocrine Disruptor Screening Program
Scientific Facts on Endocrine Disruptors
GreenBiz
| Essentials | Endocrine Disruptors
... Endocrine Disruptors
Source: GreenBiz.com. The Big Picture. A recent ... animals.
Leads. EPA Endocrine Disruptor Screening program. The ...
www.greenbiz.com/toolbox/
essentials_third.cfm?LinkAdvID=4160 - 24k
provides
up-to-date authoritative information on endocrine modulation and
endocrine disruptors
Endocrine
disruptors
LIST OF WEB SITES DEVOTED TO ENDOCRINE DISRUPTORS.
What are Endocrine
Disruptors? Nuclear ... Websites: Endocrine Disruptor,
Dept. of ...
www.ens-lyon.fr/LBMC/laudet/nurebase/
endocrine_disruptor/endocrine_disruptors.html - 18k
Endocrine/Estrogen Letter is the most comprehensive source of unbiased, accurate information about the scientific, regulatory and political issues associated with suspected endocrine disrupters
EnviroHealthAction
| Toxics and Health - Health Effects of Toxics ...
Endocrine Disruption. Any substance that
alters normal hormonal levels or
activity in the body may be labeled an endocrine disruptor.
...
www.envirohealthaction.org/ toxics/health_effects/endocrine/
- 19k
Science/Environment/Environmental
Health/Endocrine Disruptors ...
... of dioxin. url: dioxinthreat.tripod.com/;
e.hormone: At the Cutting Edge
of Endocrine Disruptor Research. Provide information
about ...
www.thedoctorslounge.net/dir/Science/Environment/
Environmental_Health/Endocrine_Disruptors/index.cgi - 63k -
CEHN:
Index of Children's Environmental Health Resources
Endocrine Disruptors. See also:
Chemicals ... Looking for articles, reports, or
scientific literature on Endocrine Disruptors? Click on
the ...
www.cehn.org/cehn/resourceguide/
endocrinedisruptors.html - 10k
New
Evidence That Endocrine Disruptors Block Sperm Function
... The US Environmental Protection
Agency's Endocrine Disruptor Screening Program,
established in 1996 under the Food Quality Protection Act to test
pesticides ...
ipm.osu.edu/trans/082_021.htm - 8k
fic.org
: Endocrine Disruptors: A False Alarm? (NewsBite)
... The EPA's Endocrine Disruptor
Screening and Testing Advisory Committee will still
develop and implement a screening program for EPA to submit to
Congress by ...
ific.org/foodinsight/1997/so/endocrinenbfi597.cfm
- 35k
Larvae
and Endocrine Disruptors
As part of the Endocrine Disruptor
Screening Program, Battelle Marine Sciences
Laboratory (MSL) staff examine larvae for normal and abnormal
development. ...
picturethis.pnl.gov/picturet.nsf/
All/5R7VPY?opendocument - 6k
Tao
Te Ching
Lao-tzu (abt.551-479 BCE)
Endocrine
Disruption and Man-Made Chemicals Time Line PBS Feb98
... President Clinton signs the Food
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Screening and ...
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Endocrine
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EPA Actions and Positions: Endocrine Disruptors
and the FQPA. EPA's Endocrine Disruptor
Screening and Testing Advisory Committee Home Page (EDSTAC). ...
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Endocrine disrupting pesticides
Endocrine disruption by estrogenic environmental pollutants
Introduction to Hormone Disrupting Chemicals
G.E.D.R.I:Global Endocrine Disruptor Research Inventory
Environment
- Endocrine Disruptors Top Links
... WWF Endocrine Disruptor Information
- Papers and speeches on how hormone disruptors
interfere with bio-chemical processes, and a suspected list of hormone ...
www.envirohealth-resource.com/Top_Science_
Environment_Environmental_Health_Endocrine_Disruptors.html - 39k
Heavy
metal: Arsenic is an endocrine disruptor - 3/5/2001 - ENN. ...
... Heavy metal: Arsenic is an endocrine disruptor.
... Most work on endocrine disruptors
has focused on chemicals that block or mimic the estrogen hormone. ...
www.enn.com/news/enn-stories/
2001/03/03052001/arsenic_42327.asp - 20k
Environment, Health and Safety Online
Endocrine
Disrupters - Find out (free) what they are, what they do ...
... They will likely be among the first compounds to
be screened in the Endocrine Disruptor
Screening Program. ... Other Resources for Endocrine Disruptor
Activities. ...
www.ehso.com/ehshome/endocrinedisrupters.htm - 26k
Chemical safety information
IPCS INCHEM offers quick and easy
electronic access to thousands of searchable full-text documents on chemical
risks and the sound management of chemicals, helping countries fulfill their
commitments under UNCED's Agenda 21, Chapter 19.
RSC (Royal Society of Chemistry) Education and Professional Development
Our
Stolen Future: Arsenic is an endocrine disruptor
... speculate that this low level endocrine
disruption may be involved in links between ...
Most hormone disruptors act by (1) affecting the amount of hormone
(either ...
www.ourstolenfuture.org/NewScience/ oncompounds/2001kaltreideretal.htm
- 24k
Pesticides as Endocrine Disruptors
Pesticides as
Endocrine Disruptors
... His article "Endocrine Disruptor
Worries Here to Stay" appeared in the September,
1997 issue of Agrichemical and Environmental News . ...
www.pmac.net/endodisr.htm - 6k -
Hormonally Active Agents in the Environment - http://www.nap.edu/catalog/6029.html
1999 National Academy of Sciences report (1) examines the
science behind the ominous prospect of "estrogen mimics" threatening health and
well-being and (2) identifies research needs. Purchase book or read it online.
Toxicological Effects of Methylmercury [pdf]
Hormone Deception - http://www.hormonedeception.com
Information by D. Lindsey Berkson explaining what hormone
disruptors are and their possible effects in the human body; steps to reduce
exposure and protect families.
Oxygen deficiency is an endocrine disruptor in fish
A lack of oxygen in waters around the world could be doing more
than just suffocating
fish: It may be acting as an endocrine disruptor and impeding
their ...
www.innovations-report.de/html/berichte/
biowissenschaften_chemie/bericht-17021.html - 50k - Sep 12, 2004
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| Wu RS, Zhou BS, Randall DJ, Woo NY, Lam PK. | Related Articles | |
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Aquatic hypoxia is an disrupter and impairs
fish reproduction. Environ Sci Technol. 2003 Mar 15;37(6):1137-41. |
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Changing World 1: Endocrine Disruptors
Science
Netlinks: 9-12 E-Sheet
... Ongoing Research. Endocrine Disruptor
Research Initiative is focused on providing
a better understanding of the effects, exposure, assessment, and risk ...
www.sciencenetlinks.com/Esheet.cfm?DocID=113 -
13k
... 2002. Atrazine, Rana pipiens, Disrupts
steroidogenesis resulting in demasculanization and hermaphroditism,
Hayes et al. 2003. Chlorinated ...
Center for Ecological Health Research
Endocrine Disruption in Fish and Birds (html)
Dartmouth's Center for Environmental Health Sciences
How arsenic acts as an
endocrine disrupter (Fig,
Research
Briefs)
Algae might be missing mercury link in aquatic food chain
A team of Dartmouth researchers is one step closer to understanding how toxic metals, specifically methylmercury, move through the aquatic food chain. Their results, published in the April 2, 2002, issue of the Proceedings of the National Academy of Sciences (PNAS) suggest that there is a link between the amount of algae in the water and the amount of mercury going up the food chain, and their findings may help explain why levels of mercury in the water don't always indicate corresponding levels in fish. MORE>>
Mercury accumulation in fish is a global public health concern, because fish are the primary source of toxic methylmercury to humans.
Algal blooms reduce the uptake of toxic
methylmercury in freshwater food webs. Paul C. Pickhardt*†, Carol L.
Folt*, Celia Y. Chen*, Bjoern Klaue‡, and Joel D. Blum‡.
*Department of Biological Sciences, Dartmouth College, Hanover, NH 03755; and
‡Department of Geological Sciences, University of Michigan, Ann Arbor, MI 48109.
PNAS | April 2, 2002 | vol. 99 |
no. 7 | 4419-4423.
[Abstract] [Full
Text]
Weis, J.S. and A.A. Khan 1991. Reduction in prey capture ability and condition in mummichogs from a polluted habitat. Trans. Amer. Fish. Soc. 120:127-129.
Khan, A.T. and J.S. Weis 1993. Differential effects of organic and inorganic mercury on the micropyle of eggs of Fundulus heteroclitus. Environ. Biol. Fish. 37: 323-327.
Weis, J.S. and P. Weis 1995. Effects of embryonic and larval exposure to methylmercury on larval swimming performance and predator avoidance in the mummichog, Fundulus heteroclitus. Can. J. Fish. Aquat. Sci. 52: 2168-2173.
Smith, G. and J.S. Weis 1997. Predator/prey interactions of mummichogs: Effects of living in a polluted environment. J. Exper., Mar. Biol. Ecol. 209: 75-87.
Zhou, T. and J.S. Weis 1998. Swimming behavior and predator avoidance in three populations of Fundulus heteroclitus larvae after embryonic and/or larval exposure to methylmercury. Aquat. Toxicol. 43: 131-148.
Weis, J.S., N. Mugue and P. Weis 1998. Mercury tolerance, population effects and population genetics in the mummichog, Fundulus heteroclitus. In: Genetics and Ecotoxicology ed. V. Forbes. Taylor and Francis Pub. pp 31-54.
The Association for Science in the Public Interest (ASIPI) is a professional society dedicated to fostering the participation of scientists in public processes, the conduct of community research and the promotion of scientific work that supports the public good.
The Scientist - How to Create a Successful Fish Tale? [html]
The SPIDER network aims to bring together researchers who are using a small fish species as an experimental model, investigating the impact of endocrine disruption on physiology and reproduction.
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Thomas, P. 2000. Disruption of the endocrine control of final oocyte maturation in teleosts by xenobiotic chemicals. pp. 165-181. In: D. Henshel, M.C. Black, and M.C. Harrass (eds.). Environmental Toxicology and Risk Assessment: Eighth Volume, ASTM STP 1364, American Society for Testing and Materials, West Conshohocken, PA.
Zhu,Y., C.D. Rice, Y. Pang, M. Pace, and P. Thomas. 2003. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. PNAS 100(5): 2231-2236 Abstract PDF
Zhu, Y., J. Bond, and P. Thomas.
Identification, classification, and partial characterization of genes
in humans and other vertebrates homologous to a fish membrane
progestin receptor. PNAS 100(5): 2237-2242.
Boudreau, M., S.C. Courtenay, D.L. MacLatchy, C.H. Bérubé, J.L. Parrott and G.J. Van Der Kraak. 2004. Utility of morphological abnormalities during early-life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of estrogenic and antiestrogenic endocrine disruption. Environ. Toxicol. Chem. 23:415-425. [Abstract]
Boudreau, M., S. Courtenay, D.L. MacLatchy, C.H. Bérubé, J.L. Parrot and G.J. Van Der Kraak. 2004. Effects of a waterborne -ethynyl estradiol) and antagonist (ZM 189, 154) on theestrogen agonist (17α early development of the estuarine killifish Fundulus heteroclitus. Environ. Toxicol. Chem. In press
MacLatchy, D.L., M.G. Dubé, M.L. Hewitt, S.C. Courtenay, R.L. Sharpe and G.J. Van Der Kraak. 2004. Development of a fish bioassay to test for hormonally-active contaminants in pulp mill effluents. In Proceedings, 5th Int. Conf. on Fate and Effects of Pulp Mill Effluents. (Ed., D. Borton). DEStech Publications, Lancaster, PA. 10pp. In press.
Sharpe, R.L.,
D.L. MacLatchy, S.C. Courtenay and G. J. Van Der Kraak. Effects of a model
androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate)
on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus
heteroclitus) bioassay. Aquat. Toxicol.
67:203-215 [Abstract]
[pdf]
MacLatchy, D.L., S.C. Courtenay, C.D. Rice and G.J. Van Der Kraak. 2003. Development of a short-term reproductive endocrine bioassay using steroid hormone and vitellogenin end points in the estuarine mummichog (Fundulus heteroclitus). Environ. Toxicol. Chem. 22:996-1008. [Abstract]
Friedman, A.S., E.K. Costain, D.L. MacLatchy, W.
Stansley and E.J. Washuta. 2002. Effect of mercury body burden on
general and reproductive health of largemouth bass (Micropterus
salmoides) from three lakes in New Jersey. Ecotox. Environ.
Saf. 52:117-122.
[Abstract]
[pdf]
UK to tackle endocrine disruptors in
wastewater
... first places in the world to actively remove
endocrine-disrupting chemicals from ... released in
July that finds that sexual disruption in fish is
widespread ...
http:/
U.K. fish exhibit intersex traits
AAFS Slide Presentation
... Therapeutic. LEVEL OF CONCERN. IS MERCURY AN
ENDOCRINE DISRUPTOR? MERCURY IS AN ENDOCRINE
DISRUPTOR. If exposure causes: ... Mercury is not
an Endocrine Disruptor.
http:/
“An Evaluation
of Methyl Mercury as an Endocrine Disruptor in
Largemouth Bass.” US Geological Survey’s Center for Aquatic Resource
Studies. 1999. ...
http:/
Endocrine Disruptor: This Webpage was compiled by Dr. Lin at The Hormone Research Center (HRC), Korea in the summer of 2004 under the sponsorship of the NIH-MIRT program. Dr. Lin would like to thank Dr. H-B Kwon (Director, HRC), Dr. R-S Ahn, faculty and staffs at the HRC for their input and hospitality
DISCLAIMER (Large Print Size) : The views, opinions, and conclusions expressed in this page or document are those of the author and not necessarily those of Barry University or its officers and trustees. The content of this material has not been reviewed or approved by Barry University, and the author is solely responsible for its content. The author is NOT responsible for non-Barry websites (External Links). Since they are maintained by another organization, they can be changed without notice to the author. Therefore, endorsement of the external links by the author is not implied. Last Updated: 25 October 2004
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