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BIO 475 (01)      SEMINAR  

              

 

NCBI: PubMed Medline Citation Search Nature Google MEDLINEplus Health Information U.S. National Library of Medicine Gateway Online Mendelian Inheritance in Man: OMIM Barry Electronic Journal Service Journals @  O V I D Full-Text PubMed Central Full-Text Go to ScienceDirect FullText Biological Abstract Database JAMA & Archives:Am Medical Assoc Journals  Free Medical Journal.com MedBioWorld: Medical Reference SiteScienceDaily Magazine OCLC FirstSearch Medline PubMed LinkOut to Barry Full Text Collection

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BIO 475  (01)    SEMINAR    Course Syllabus

Spring 2005    (Three Credit-Hours)

8:00 AM- 8:50 AM      Mon., Wed. and Fri.              Wiegand  Rm234

Dr. Yu-Wai Peter Lin

Office/Lab:         SNHS Rm 330,          Ph: (305) 899-3226

E-mail:   plin@mail.barry.edu   emailed.gif (14893 bytes)

 

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Office Hours:

    M  &  9:00 AM - 11:30 AM;      

   

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Seminar Class Distribution List (Bucmail):

            BIO-475-01-0501@mail.barry.edu

How do I send email directly without searching the global address book ?

The class list addresses are created using the following format:

Course-ID-Section-YearTerm@mail.barry.edu

For example, Accounting 336 01 held in Fall 2001 would have ACC-336-01-0101@mail.barry.edu as the e-mail address.

Will everyone be able to send messages to my class list ?

No, only members (students registered in the course) of the list will be able to send to the class list.  Instructors are added as members to the class list, allowing them to send messages. 

 

   

Symposium

 

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CELEBRATING STUDENT EXCELLENCE; KNOWLEDGE EMPOWERS

MARC U*STAR 20th Anniversary Symposium

MARC U*STAR Celebrates 20th Anniversary at Barry

February 13, 2003

MARC Symposium Registration

 

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Guest Speaker

March 21, 2003

Dr. Richard Falvo

Click on the slide below to preview Dr. Falvo's presentation

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April 23, 2003

Dr. Xiaotang Hu

Click here to preview Dr. Hu's presentation

CELL CYCLE CONTROL AND CANCER

 

 

 

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Course Outline:

Presentation of reports, discussions, lectures, and papers on selected topics in biology.

 

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Course Goals and Objective:

Goals -- The major goal of the Seminar Course is to acquire an understanding of the Scientific Method and how to apply it through the use of Library Research techniques.   A secondary aim is to familiarize students with current scientific literature and the use of the vast biomedical resources on the World Wide Web for research.

Objectives -- Upon completion of this course the student should be able to:

  1. increase analytical and critical thinking skills by reading, interpreting and discussing current scientific journal articles in the biomedical field.
  2. comprehend and organize ideas, apply and analyze information, evaluate and solve problems.
  3. write and present a Scientific Review, based on both Primary and Secondary Resources,  in a scholarly fashion.

 Results of the "Course Objective Writing Contest"

 

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Instructional Methods:

This course will follow a weekly journal club format. Recent scientific articles in biomedical research will be assigned in advance to each student and discussed in class. The lecture portion of the course will consist of oral presentations given by the instructor and supplemented with overhead transparencies and AV slides. Peer review, cooperative learning, and active discussions with the students are encouraged. Term paper and homework will be assigned. Critical reading and discussion of recent scientific journal articles will be part of the regular student activities.

Computer assignments (HyperCELL), internet connection to biology web site on the World Wide Web (The Biology Place), online scientific journals (Current Opinion in Cell Biology- http://biomednet.com/cbiology/cel), CD-ROM (Current Content), Medline Search (Internet Grateful Med- http://igm.nlm.nih.gov), web connection to the National Library of Medicine, National Center for Biotechnology Information (PubMed- www.ncbi.nlm.nih.gov/pubmed) and simulations (PCGene) will be used during the course. Students are required to give at least two presentations during the semester.

 

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Text:

Subscription to “Science” magazine required 

  (Required subscription)

http://www.sciencemag.org/subscriptions/signedin.shtml  

 

Copyright © 1999 by the American Association for the Advancement of Science

http://www.sciencemag.org/

 

No required text. We will utilize journal articles for our weekly seminar discussion. The Barry Library currently holds a number of science journals with articles on scientific research. These include: Proceedings of the National Academy of Science (PNAS), the Quarterly Review of Biology, Journal of Experimental Zoology, Journal of Experimental Biology, Nature, and Science; just to name a few.

We will also utilize a number of on-line journals through the internet (BioMednet- http://biomednet.com, Medline- http://igm.nlm.nih.gov, NIH AIDS information resources, The Biology Place- www.biology.com etc.)

For references and links to some hot biology sites on the Internet, please visit the School of Natural and Health Science Homepage on the World Wide Web at http://www.barry.edu/snhs/snhs_menu.html   [and click on Biology Link]

I will give out photo-copies of journal articles for the reading assignment, therefore a fee ($10-$15) for making photo-copies is required from each student taking the course.

 

 

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Disability Statement:

Students with documented special learning needs may want to infrom the instructor so that accommodations may be made, or contact the Barry Office of Services for Students with Disabilities 305-899 3489

 

 

bulletStudent Behavior Statement:

All Barry University students are expected to behave according to accepted norms that ensure a climate wherein all can exercise their right to learn. Disruptive behavior is not acceptable in the classroom.  Students engaging in such behavior may be asked to leave or may be removed from the class by security personnel.  Actions such as violence, shouting, use of cell phones and/or beepers, using profanity, interrupting, and any other behavior that the instructor believes creates an unpleasant environment in the classroom will be grounds for withdrawal from the course, judicial proceedings, or failure of the course.

 

 

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BIOLOGY GRADING SCALE

A = 90-100%

B = 80-89%

C = 70-79%

D = 60-69%

F = 0-59%

Your Final Grade for this course will be determined as follows:

Term Paper (1 st. to 3 rd draft) = 100 points total

        Due: Nov. 14, 2003

Term Paper (Final draft) = 200 points

        Due: Dec. 05, 2003

Three (3) Seminar Reports = 100 points each (300 total points)

        1 st Report due: Sep. 08, 2003

        2 nd Report due: Oct. 06, 2003

       3 rd Report due: Nov. 03, 2003

Journal Club Participation and Presentation = 150 points

Homework/Library/Quizzes = 150 points

Subjective: Class participation, attendance, etc. = 100 points

Total = 1000 total points possible

Grade = Total points earned / 1000 x 100%

Note: All exams, quizzes and written assignments are the property of the School of Natural and Health Sciences, and will not be returned to the student.   Graded assignment will be returned for review within 2 weeks after submission.

 

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Dishonesty Policy:

Students should be aware that cheating will not be tolerated. Any student caught giving or receiving assistance during an exam, or using cheat sheet, etc. will receive a grade of ZERO for that exam. This zero grade may not be dropped or made up; and WILL be used when determining the student's final grade. Any student caught cheating a second time will receive a grade of F for the course and will be referred to his/her Dean for disciplinary action. The same is true with respect for quizzes. A plagiarized written assignment will receive a grade of ZERO.

(For further information concerning the dishonesty policy, please refer to your Barry University 2002-2003 Catalog)

 

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Term Paper and Homework/Library Assignments:

There will be one term paper (worth 300 points), three (3) seminar reports (worth 100 points each) and three (3) homework/library assignments (worth 50 points each) during the semester. These assignments are important to your grade in the course and are intended to help guide your studying and to familiarize you with the recent and cutting edge scientific literature and research. Specifics regarding the term paper assignments are as follow:

    a)    Use 'Writing Papers in the Biological Sciences' by Victoria E. McMillan as the official guide.

    b)    Your paper is not meant to be a laboratory research paper (for example, you do not need to organize sections such as "Methods", "Results", etc).  Instead, follow the guidelines and examples stated in Chapter 5 of McMillan's book (Writing a Review Paper).

    c)    All papers must be typed (double-spaced).

It is a good idea to ask me if there may be a question as to whether your paper is focused in the right direction.  (I will be willing to review typed rough drafts up until November. 10, 2003).

Any assignment turned in late will be worth a maximum of 1/2 credit.   Graded assignment will be returned for review within 2 weeks.

 

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Class Attendance

Class Attendance is Mandatory

You are expected to attend and actively participate in all classes. The student who is consistently late or absent will not have the same opportunities to ask questions as punctual students who attend each lecture and seminar. Therefore, consistent tardiness and/or consistent absence will result in a significantly lower evaluation on class participation. Daily sign-in sheets will be provided for the student's protection. A record of students who arrive late for lecture will be kept. You are responsible for all material covered in lectures or labs. If you miss classes, you cannot expect to do well in this course.

ABSENCE FROM CLASS IS NO EXCUSE FOR

MISUNDERSTANDINGS ABOUT ASSIGNMENTS OR QUIZZES

 

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Links  and   Assignments

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bulletDr. Lin's Biology Links (framed)
bulletDr. Lin's Biology Links (unframed version)
bullet Definitions of Library Vocabulary and Terms
bulletLibrary Research using Primary Sources
bullet What are Primary Sources? (Yale Univ. Library)
bulletThe Joy of Teaching, JT: Pharisees' Question (Anticipatory Set, AS; Cognitive Domain, CD; Educational Objective, EO); Critical Thinking, CT; Educational Psychology Interactive (Dr. Huitt, Valdosta State Univ.)
bullet The Scientific Method Science is best defined as a careful, disciplined, logical search for knowledge about any and all aspects of the universe, obtained by examination of the best available evidence and always subject to correction and improvement upon discovery of better evidence. What's left is magic. And it doesn't work. -- James Randi
bulletAssignments

 

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U.S. National Library of Medicine Gateway

http://gateway.nlm.nih.gov/gw/Cmd

The NLM Gateway is a Web-based system that lets users search simultaneously in multiple retrieval systems at the U.S. National Library of Medicine (NLM). It allows users of NLM services to initiate searches from one Web interface, providing "one-stop searching" for many of NLM's information resources or databases. It is being developed by the Lister Hill National Center for Biomedical Communications (LHNCBC) at the National Library of Medicine (NLM), a part of the National Institutes of Health (NIH).

 

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Medline Search:

            (PubMed- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi)

To limit PubMed search to Barry Library Full Text holding, use the link below:

PubMed LinkOut to Barry Full Text Collection

Barry’s full text link-out collection will appear in search box as loprovflbulib[SB]. You can then type your search term, example: loprovflbulib[SB] AND diabetic foot (remember that AND must be in capital letters). To display full-text simply click on Barry logo at top of record

 

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Medline Plus  For the Public: MEDLINEplus Health Information

         http://medlineplus.gov/      

 

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Online Mendelian Inheritance in Man

OMIM online database for genetic diseases- www.ncbi.nlm.nih.gov/Omim

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National Library of Medicine-http://www.nlm.nih.gov

bulletNational Center for Biotechnology Information http://www.ncbi.nlm.nih.gov/

 

bulletCenters for Disease Control and Prevention http://www.cdc.gov/

 

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Medical Dictionary Search Engine http://www.books.md/

 

 

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AIDS  LINKS: Acquired Immunodeficiency Syndrome 

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Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome (AIDS) - 1999 (Full Text)

AIDS Case Definition (CDC)  

 

bulletMedscape - AIDS
bulletJAMA - HIV Site
bulletAMA Home Page
bullet The World-Wide Web Virtual Library
bulletThe Body: A Multimedia AIDS and HIV Information Resource
bullet AIDS Meds.com
bullet"Human retroviruses and AIDS Compendia pdf"HIV Databases
bulletUnited Nation -AIDS
bulletThe Official U.S. Government Definition Of "AIDS" (1993)
bulletAEGiS logo
bullet AEGiS AIDS Education Global Information System
bulletLatin America and Caribbean HIV/AIDS Regional Initiative (LACRI).
bullet Glossary of HIV/AIDS-Related Terms  (Dept. of Health and Human Services)
bullet MEDLINEplus Medical Encyclopedia: AIDS 
bullet AIDS Prevention and Vaccine Research (AIDScience)
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A review of HIV transmission  through breastfeeding, pdf (Joint United Nations Programme on HIV/AIDS)

The Cell Place  Retrovirus HIV Reproductive Cycle http://occawlonline.pearsoned.com/bookbind/pubbooks/cellplace/chapter19/deluxe.html

 

 

 

 

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Compendia

Morbidity and Mortality Weekly Report

http://www.cdc.gov/mmwr/

 

25 Notable HIV and AIDS Reports Published in the Morbidity and Mortality Weekly Report (MMWR)

http://www.cdc.gov/mmwr/hiv_aids20.html

 

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 NIH Logo     National Institutes of Health, DHHS  Image of Main Administration Building

20 Years of AIDS Research   In their own wordsdocuments how NIH researchers answered such questions when asked to recall the early days of HIV/AIDS. In launching this Web site, we commemorate the 20-year struggle to confront the deadly HIV/AIDS pandemic.

To see the animated version requires Macromedia Shockwave Player.
If you want to see a version that is not animated, please click here

http://aidshistory.nih.gov/

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bulletElectronic Databases & Journals at Barry

 

subtitle-top.GIF (11119 bytes)

 http://bucwis.barry.edu/libraryservices  (On-Campus access only)

The Monsignor William Barry Memorial Library subscribes to nearly 150 electronic databases.

Most of our databases are available over the Internet.  Online access to these databases is possible from any networked computer on the main campus or from any off-campus patron who has the VPN remote access software.  

Electronic Databases

Electronic Databases http://bucwis.barry.edu/libraryservices/catalogresources/eDatabaseSubject.htm

Electronic Journals (BioMedical)
Electronic Journals
http://bucwis.barry.edu/libraryservices/catalogResources/eJournalSubject/biomedical.htm

 

 

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Copyright © 1999 by the National Academy of Sciences.

You can now get full text and search Proceedings of the National Academy of Sciences online by going to following web site: http://www.pnas.org

User Name is: comet

Password is: ******

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The Lancet Interactive software and compilation The Lancet Ltd. All rights reserved. The Lancet is an Elsevier Science trademark.

You can get full text and search Lancet online by going to: http://www.thelancet.com

Click on "subscribers" and enter:

Username: medbarry

Password: ********

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© Copyright 1999 Massachusetts Medical Society.

 

You can get full text and search The New England Journal of Medicine online by going to: http://www.nejm.org/content/index.asp

Click on "LOG ON TO FULL TEXT" and enter:

Username: BARRYMED

Password: ***********

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Copyright © 1999 by the American Association for the Advancement of Science

Search and View Full-text articles:

http://www.sciencemag.org/

User Name:  peterlin              Password: ********

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bullet to Nature home pageMacmillan Magazines

Nature © Macmillan Publishers Ltd 1999 Registered No. 785998 England.

Search and View Full-text articles:

http://www.nature.com/Dynasearch/App/DynaSearch.taf?target=journals

User Name:  chipola              Password: ******

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bulletAnnual Review of Microbiology

Copyright © 2000 by Annual Reviews

Search and View Full-text articles:

http://micro.annualreviews.org/search.dtl

(Full-text Only Accessible using On-Campus Computer)

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bulletAnnual Review of Physiology

Copyright © 2000 by Annual Reviews

Search and View Full-text articles:

http://physiol.annualreviews.org/search.dtl

(Full-text Only Accessible using On-Campus Computer)

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bulletJournal of Biological Chemistry

© 2000 by The American Society for Biochemistry and Molecular Biology, Inc.

ISSN 1083-351X

Home

Home Help [Feedback] [For Subscribers] [Archive] [Search]

Search and View Full-text articles:

http://www.jbc.org/search.dtl

(Full-text Only Accessible using On-Campus Computer)

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Journal of Applied Physiology

Copyright © 2000 by the American Physiological Society.
ISSN: 1522-1601

Home[For Subscribers] [Browse & Search]

Search and View Full-text articles:

http://jap.physiology.org/all.shtml

(Full-text Only Accessible using On-Campus Computer)

 

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Genetics

A periodical record of investigations bearing on heredity and variation

Copyright © 2000 by the Genetics Society of America.

Genetics  http://www.genetics.org/

(Full-text Only Accessible using On-Campus Computer)

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The Journal of Heredity

Latest Issue

Copyright© Oxford University Press

http://www3.oup.co.uk/Architext/AT-hdb-jheredquery.html

The Journal of Heredity use Excite Search to do the searching

(Full-text Only Accessible using On-Campus Computer)

 

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JCB Online

Copyright © 2000 by the Rockefeller University Press.

The Journal of Cell Biology  http://www.jcb.org/

(Full-text Only Accessible using On-Campus Computer)

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http://www3.interscience.wiley.com/cgi-bin/jtoc?ID=28741

Online ISSN: 1097-0142    Print ISSN: 0008-543X
Cancer   Copyright © 2000 American Cancer Society

(Full-text Only Accessible using On-Campus Computer)

 

 

 

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Diagram of Mature HIV
by Andrew Davies

 

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Assignments:

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Go to: Reading Assignment for the Week of September 15, October 1, November 3, 2003

 

Reading Assignment for the Week of September 1, 2003

Review Article

How Does HIV Cause AIDS ?  Robin A. Weiss, Science 260:1273-1279 (May 23 1993) [Full Text from JSTOR, pdf format]

Search Science Archives Prior To October 1995

Science issues prior to October 1995 are available online through JSTOR, the Journal Storage Organization. AAAS Members have free access to Science at JSTOR as a member benefit. Go to http://aaasmember.org, sign in as a member, and then click on the link to JSTOR. You must access JSTOR through aaasmember.org.

 

 

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biologyplace.gif (1600 bytes)

The Biology Place: http://www.biology.com

User ID- ******

Password- *********

Interactive Learning Activities:

HomeWork Assignment #1 (Due Jan 29, 50 Points)

Cell to Cell and Person to Person:
Investigating AIDS and HIV

by John Postlethwait, University of Oregon
© 1997, Peregrine Publishers, Inc., All Rights Reserved


Part I: The Discovery and Epidemiology of AIDS
Part II: Investigating HIV so as to Devise AIDS Therapies

http://www.biology.com/learning/hiv2/introduction.html

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Reading Assignment for the Week of September 15, 2003

Primary Source Article

http://www.sciencemag.org/subscriptions/signedin.shtml  

 

Copyright © 1999 by the American Association for the Advancement of Science

User Name:            Password: ********

 

 

Dean et.al. 1996, Science, 273:1856-1862, Fig.2

 

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene.  Michael Dean et.al.  Science (Sept 27 1996) 273:1858-1862   http://www.sciencemag.org    [Abstract] [Full Text] [html version]

 

Scientific American   (http://www.sciam.com)

   

© 1996, 1997, 1998, 1999, 2000 Scientific American, Inc. All rights reserved.

click here!

The Search of AIDS-Resistance Gene. 

Stephen J. O'Brien and Michael Dean.   Scientific American, September, 1997  (http://www.sciam.com/0997issue/0997obrien.html)

[PDF version]

 

 

Co-Receptors for HIV: CKR5 (Project inform)
http://www.projinf.org/fs/dp-CKR5_Fusin.html

 

Structure of the CC-chemokine, RANTES 

http://www.urmc.rochester.edu/smd/mbi/chime/ranframe.html

http://bioresearch.ac.uk/whatsnew/detail/1099788.html

 

  Koning FA, Kwa D, Boeser-Nunnink B, Dekker J, Vingerhoed J, Hiemstra H, Schuitemaker H. Related Articles, Links
Abstract Decreasing Sensitivity to RANTES (Regulated on Activation, Normally T Cell-Expressed and -Secreted) Neutralization of CC Chemokine Receptor 5-Using, Non-Syncytium-Inducing Virus Variants in the Course of Human Immunodeficiency Virus Type 1 Infection.
J Infect Dis. 2003 Sep 15;188(6):864-72. Epub 2003 Sep 04.

 

 

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Reading Assignment for the Week of October 1, 2003

     

Fig. 2. The effect of  cell-specific suppression of

GAD expression on the development of diabetes and insulitis

Control of Autoimmune Diabetes in NOD Mice by GAD Expression or Suppression in β Cells
Ji-Won Yoon, Chang-Soon Yoon, Hye-Won Lim, Qi Quan Huang, Yup Kang, Kwang Ho Pyun, Kensuke Hirasawa, Robert S. Sherwin, and Hee-Sook Jun
Science 1999 May 14; 284: 1183-1187. (in Reports) [Abstract] [Full Text .html] [Full Text .pdf]

 

Perspective

Gadfly autoantigen. Autoimmune diabetes develops in nonobese diabetic (NOD) mice when peptides derived from glutamic acid decarboxylase (GAD), which is expressed by the insulin-producing b-islet cells (blue) of the pancreas, are presented by antigen presenting cells (APCs) to T cells (A).

 

GAD and Type I Diabetes
Science 1999 May 14; 284: 1085k (in This Week in Science) [Summary][html version]

 

GAD, a Single Autoantigen for Diabetes

Harald von Boehmer and Adelaida Sarukhan* [html version]

http://www.sciencemag.org/cgi/content/full/284/5417/1135

Science Volume 284, Number 5417 Issue of 14 May 1999, pp. 1135 - 1137
©1999 by The American Association for the Advancement of Science.

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Reading Assignment for the Week of November 3, 2003

 

 

 

Fig. 1. Effect of CX3CR1 variants on HIV disease progression

 

Rapid Progression to AIDS in HIV+ Individuals with a Structural Variant of the Chemokine Receptor CX3CR1

Sophie Faure et.al.
Science Mar 24 2000: 2274-2277. [Abstract] [Full Text .html]  [Full Text .pdf]

 

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REVIEW

The Genome Sequence of Drosophila melanogaster

http://www.sciencemag.org/feature/data/genomes/landmark.shl

     

             Mar 24 2000
             Vol. 287, No. 5461  The Drosophila Genome           

 

Abstract     Full Text   

Coding Content of the Drosophila Genome

 

 

 

 

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Reading Assignments :

Review Article

How Does HIV Cause AIDS ?  Robin A. Weiss, Science 260:1273-1279 (May 23 1993)

 

Primary Source Article

http://www.sciencemag.org/subscriptions/signedin.shtml  

 

Copyright © 1999 by the American Association for the Advancement of Science

User Name:            Password: ********

 

 

Dean et.al. 1996, Science, 273:1856-1862, Fig.2

 

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene.  Michael Dean et.al.  Science (Sept 27 1996) 273:1858-1862   http://www.sciencemag.org    [Abstract] [Full Text] [html version]

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Use of Chemokine Receptors by Poxviruses
Alshad S. Lalani, Jennefer Masters, Wei Zeng, John Barrett, Rajeet Pannu, Helen Everett, Christopher W. Arendt, and Grant McFadden
Science (Dec 3 1999) 286:1968-1971. [Abstract] [Full Text]
 

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Scientific American   (http://www.sciam.com)

   

© 1996, 1997, 1998, 1999, 2000 Scientific American, Inc. All rights reserved.

click here!

The Search of AIDS-Resistance Gene. 

Stephen J. O'Brien and Michael Dean.  

Scientific American, September, 1997 

(http://www.sciam.com/0997issue/0997obrien.html) [PDF version]

 

 

 

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Copyright 1998, Peregrine Publishers, Inc. All Rights Reserved.
Recent Research on Co-receptor CKR5

http://www.biology.com/learning/hiv2/entry5.html

 

 

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This Week in Science 

Volume 286, Number 5447, Issue of 10 December 1999
©1999 by The American Association for the Advancement of Science.

Finding the Right Place to Work[To top]

How do B cells and T cells coordinate their movements so that lymphocytes with the appropriate specificities are at the right place at the right time? Specific interactions do occur, and Cyster (p. 2098) reviews how the chemokine highway helps direct traffic. Chemokines act as attractants and are expressed in temporally and physically discrete fashion. The receptors for chemokines are expressed only by those cells best able to mount an immune response. A specific case of immune cell localization is presented by Randolph et al. (p. 2159), who report that different subsets of T cells tend to be in discrete locations in the spleen, an organ that also hosts B cells. This T cell localization depends on the chemokine receptor CCR7, a receptor for the chemokine SLC, which TH1 cells express. If TH2 cells are forced to express CCR7, not only do they migrate to the wrong spots in the spleen, but they no longer provide help for B cells. Thus, CCR7 seems critical for appropriate localization of T cells to ensure an adequate immune response.

Review

Chemokines and Cell Migration in Secondary Lymphoid Organs
Jason G. Cyster
Science (Dec 10 1999) 286: 2098-2102. [Abstract] [Full Text]

Research Article

The Role of CCR7 in TH1 and TH2 Cell Localization and Delivery of B Cell Help in Vivo
David A. Randolph, Guangming Huang, Cynthia J. L. Carruthers, Lindsay E. Bromley, and David D. Chaplin
Science (Dec 10 1999) 286: 2159-2162. [Abstract] [Full Text]

 

 

 

 

 

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Example of Library Research:

Medline Search

bulletPubMed NLM's search service to access the 9 million citations in MEDLINE and Pre-MEDLINE 
bullet(with links to participating on-line journals), and other related databases.

   http://www.ncbi.nlm.nih.gov/PubMed/

 

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National Library of Medicine-http://www.nlm.nih.gov

NLM Home  MEDLINEplus Health Information

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Term Paper Preparation  --Library Research

bulletStep One:::  Research Topics and Outlines

Example:

Title:  Mycoplasma penetrans and AIDS, a possible interaction to enhance the progression through Immune Activation

 

I. Introduction

A. General background of M. penetrans 1. What is it? 2. Where is it found? 3. Properties concerning cell colonization, cell invasion and cytopathicgenicity

II.      A. The relation between AIDS and M. penetrans

1. AIDS related mycoplasma species may act as immunomodulatory cofactors by eliciting inappropriate cytokine gene expression in B cell lines -cell death inducing activity

2. Ability of the mycoplasma to activate different functions of the immune system -tumor necrosis factor alpha -activation of HIV-LTR mediated transcription

3. Defenses against immune response -membrane lipoproteins -surface capsular material

III. Conclusion

A. Increased knowledge about mycoplasma due to the development of specific detections assays

B. The predominance in homosexual practices in HIV seropositive subjects.

C. Treatment- antiobiotic susceptibilities

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bulletStep Two:::  Medline Search

Example:

Key Concepts or Key Words

Mycoplasma penetrans, AIDS,  HIV, Immune Activation, cytopathicgenicity, immunomodulatory cofactors, cytokine gene expression, B cell, tumor necrosis factor alpha, HIV-LTR,  immune response, membrane lipoproteins, detections assays,  homosexual, HIV seropositive,  antiobiotic susceptibilities

 

 

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

 

     

PubMed is the National Library of Medicine's search service that provides access to over 10 million citations in MEDLINE, PreMEDLINE, and other related databases, with links to participating online journals.
   Books linked to PubMed      The New PubMed!
In collaboration with book publishers, NCBI is adapting books for the web and linking them to PubMed. The first book, Molecular Biology of the Cell by Alberts et al., is now available.   This new version of PubMed has a single search interface with pull-down menus that display search field limits, indexes, your search history, and a clipboard for gathering selected articles. See help and FAQ for more information.

PubMed  Search  using  the  following Key Words:

Mycoplasma penetrans, AIDS,  HIV

Search for

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

Sample of Search Results:

Review Articles

: Blanchard A. Related Articles
Mycoplasmas and HIV infection, a possible interaction through immune activation.
Wien Klin Wochenschr. 1997 Aug 8;109(14-15):590-3. Review.
PMID: 9286065; UI: 97432061

Primary Soruce Articles

1 : de Cordova CM, Takei K, Rosenthal C, Miranda MA, Vaz AJ, da Cunha RA. Related Articles
Evaluation of IgG, IgM, and IgA antibodies to Mycoplasma penetrans detected by ELISA and immunoblot in HIV-1-infected and STD patients, in Sao Paulo, Brazil.
Microbes Infect. 1999 Nov;1(13):1095-1101.
[Record as supplied by publisher]
PMID: 10572313
2 : Hussain AI, Robson WL, Kelley R, Reid T, Gangemi JD. Related Articles
Mycoplasma penetrans and other mycoplasmas in urine of human immunodeficiency virus-positive children.
J Clin Microbiol. 1999 May;37(5):1518-23.
PMID: 10203515; UI: 99221782
3 : Loubinoux J, Piroux V, Guyot PY, Amiel C, Catelle A, Rihn B, Canton P, Le Faou A. Related Articles
Genital mycoplasmas in patients with acquired immunodeficiency syndrome.
New Microbiol. 1998 Oct;21(4):403-5.
PMID: 9812323; UI: 99028857
4 : da Cunha RA, Takei K, Vaz AJ, Rosenthal C. Related Articles
Detection of mycoplasmas in urethral swabs from HIV-1 infected patients and control individuals using culture techniques and polymerase chain reaction.
Rev Inst Med Trop Sao Paulo. 1998 Jan-Feb;40(1):1-5.
PMID: 9713129; UI: 98378751
 
 

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NIAID Logo   Activities

Division of Acquired Immunodeficiency Syndrome

 

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Step Four:::  Final  Presentation

 

Example of MicroSoft PowerPoint Presentation by Students in the Fall 1998 Seminar Class

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Click here to start the MicroSoft PowerPoint Presentation

 

 

 

 

 

 

 

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Dr. Lin's Bookmarks

 

Medline, NIH, CDC, GOV.

World Health Organization

 

CDC

Ctr Disease Control Prevention CDC
Morbidity & Mortality Weekly Report

 

National Library of Medicine

Internet Grateful Med - Medline
Welcome to PubMed-Nat Lib Med
U.S. National Library of Medicine (NLM)

Database Search, Public Library, Journals

Database search

Internet Grateful Med - Medline
WebSPIRS: Database Selection
Firstsearch Database Access
Welcome to PubMed-Nat Lib Med

Magazines

NGS - National Geographic Online
Scientific American
Discover Magazine
New Scientist Planet Science - News, jobs and more from the leading weekly magazine

Journals

Gateway

Medscape
Welcome to BioMedNet
IDEAL-Electronic Access Library
APNet Academic Press
John Wiley & Sons, Inc., Publishers
Biology of Reproduction ISSN 0006-3363
The British Medical Journal
New England Journal of Medicine
The EMBO Journal Online
Experimental Cell Research
Welcome to Science Online
Nature - International weekly journal of science
Nature Genetics
Genes & Development
Nucleic Acids Research Online
JAMA - J American Medical Assoc
JPET-J Pharma Exp Theraput
Development
Journal of Cell Science
The Journal of Experimental Biology
Library of Congress
U.S. National Library of Medicine (NLM)
MBL/WHOI Library Mariner Online Catalog
New York Public Library
National Library of Canada - Bibliothèque nationale du Canada
Welcome to the Electric Library
The Internet Public Library
Florida Distance Learning Library Initiative
Fl. DOS-Library & Information Services
OCLC Online Computer Library Center
 
 
 

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Full-Text Electronic Journal Holdings

Monsignor William Barry Memorial Library                 Home

Full Text:  Delay of 6 to12 Months due to publisher restriction 

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Cancer Research Aids Online JAMA & Archives:Am Medical Assoc Journals  Proceedings of the National Academcy of Sciencess  The Federation of American Societies for Experimental Biology Journal  Journal of Biology  The Journal of Experimental Biology  ScientificAmerican.com The Quarterly Review of Biology   

 

AllTheWeb: WWW Search Engine NCBI: PubMed Medline Citation Search MEDLINEplus Health Information Gene Gateway
Nature U.S. National Library of Medicine Gateway Barry Electronic Journal Service Journals @ O V I D  Full-Text PubMed Central Full-Text Go to ScienceDirect FullText Biological Abstract Database  OCLC FirstSearch Medline  Free Medical Journal.com Find Articles.com MedBioWorld: Medical Reference Site ScienceDaily Magazine

Google
Search WWW Internet     Search Dr.Lin's Instructional Web 

 

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Medline Search:

            (PubMed- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi)

PubMed entry on Library Web Page (see below) has been updated to include description on how to limit search to print and electronic subscriptions held by Barry Library.

 MEDLINE in PubMed - Note: to limit search to full text
1) go to left blue navigation bar and, under PubMed Services, click on LinkOut 
2) under left blue navigation bar heading for Lists click on Libraries
3) click on Southeastern Atlantic Region and
4) click on LinkOut Collection for Barry University Library.

To limit PubMed search to Barry Library Full Text holding, use the link below:

PubMed LinkOut to Barry Full Text Collection

Barry’s full text link-out collection will appear in search box as loprovflbulib[SB]. You can then type your search term, example: loprovflbulib[SB] AND diabetic foot (remember that AND must be in capital letters). To display full-text simply click on Barry logo at top of record

 

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DISCLAIMER (Large Print Size) : The views, opinions, and conclusions expressed in this page or document are those of the author and not necessarily those of Barry University or its officers and trustees. The content of this material has not been reviewed or approved by Barry University, and the author is solely responsible for its content. The author is NOT responsible for non-Barry websites (External Links). Since they are maintained by another organization, they can be changed without notice to the author. Therefore, endorsement of the external links by the author is not implied.

 

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